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DDR1 Protein (AA 22-415) (His tag)

DDR1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274462
发货至: 中国
  • 抗原 See all DDR1 蛋白
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    蛋白类型
    Recombinant
    产品特性
    AA 22-415
    宿主
    • 18
    • 6
    • 2
    • 1
    小鼠
    资源
    • 9
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This DDR1 protein is labelled with His tag.
    原理
    Mouse DDR1 Protein
    序列
    Asp22-Ala415
    产品特性
    Recombinant Mouse DDR1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp22-Ala415.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product DDR1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
    别名
    DDR1 (DDR1 产品)
    别名
    CG11573 Protein, CG13984 Protein, CG13985 Protein, CG33531 Protein, CG9488 Protein, CG9490 Protein, CT33540 Protein, DDR Protein, Dmel\\CG33531 Protein, Dmel_CG13984 Protein, 6030432F18 Protein, AI323681 Protein, CD167a Protein, Cak Protein, Nep Protein, PTK3A Protein, CAK Protein, CD167 Protein, EDDR1 Protein, HGK2 Protein, MCK10 Protein, NEP Protein, NTRK4 Protein, PTK3 Protein, RTK6 Protein, TRKE Protein, Drd1 Protein, PTK3D Protein, Discoidin domain receptor Protein, discoidin domain receptor family, member 1 Protein, discoidin domain receptor tyrosine kinase 1 Protein, Ddr Protein, Ddr1 Protein, DDR1 Protein
    背景
    Discoidin domain receptor1 (DDR1) is a collagen activated receptor tyrosine kinase and an attractive anti-fibrotic target. Its expression is mainly limited to epithelial cells located in several organs including skin, kidney, liver and lung. DDR1's biology is elusive, with unknown downstream activation pathways, however, it may act as a mediator of the stromal-epithelial interaction, potentially controlling the activation state of the resident quiescent fibroblasts.
    分子量
    44.9 kDa. Due to glycosylation, the protein migrates to 60-65 kDa based on Tris-Bis PAGE result.
    途径
    RTK signaling, Smooth Muscle Cell Migration
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