M-CSF/CSF1 Protein (AA 33-255) (His tag)
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- 抗原 See all M-CSF/CSF1 (CSF1) 蛋白
- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 33-255
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宿主
- Cynomolgus
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资源
- HEK-293 Cells
- 标记
- This M-CSF/CSF1 protein is labelled with His tag.
- 原理
- Cynomolgus M-CSF/CSF-1 Protein
- 序列
- Glu33-Leu255
- 产品特性
- Recombinant Cynomolgus M-CSF/CSF-1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu33-Leu255.
- 纯度
- > 95 % as determined by Tris-Bis PAGE
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 0.889 μM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product CSF1 蛋白
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Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) protein
CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) protein (His-Avi Tag)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) protein (His-Avi Tag,Biotin)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190), (Isoform 3) (Active) proteinCSF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as analyzed by non-reducing SDS-PAGE. Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (Active) proteinCSF1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant SDS, Func Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (Active) proteinCSF1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-187) (Active) proteinCSF1 宿主: 小鼠 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) (Active) protein (His tag)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) (Active) protein (His tag,AVI tag,Biotin)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) protein (His tag)CSF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
- 别名
- M-CSF (CSF1 产品)
- 别名
- CSF-1 Protein, MCSF Protein, C87615 Protein, Csfm Protein, op Protein, csf1-1 Protein, zgc:172186 Protein, CSF1 Protein, csf1-2 Protein, zgc:158436 Protein, colony stimulating factor 1 Protein, colony stimulating factor 1 (macrophage) Protein, colony stimulating factor 1a (macrophage) Protein, macrophage colony-stimulating factor 1 Protein, macrophage colony stimulating factor Protein, colony stimulating factor 1b (macrophage) Protein, CSF1 Protein, Csf1 Protein, csf1a Protein, LOC396599 Protein, LOC100860895 Protein, csf1b Protein
- 背景
- CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of osteoclast progenitors.CSF-1 is cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand.
- 分子量
- 26.26 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Tris-Bis PAGE result.
- NCBI登录号
- XP_045221641
- 途径
- RTK signaling
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