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CD70 Protein (AA 45-195) (Fc Tag)

CD70 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7274243
发货至: 中国
  • 抗原 See all CD70 蛋白
    CD70 (CD70 Molecule (CD70))
    蛋白类型
    Recombinant
    产品特性
    AA 45-195
    宿主
    • 34
    • 8
    • 1
    • 1
    • 1
    小鼠
    资源
    • 25
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This CD70 protein is labelled with Fc Tag.
    原理
    Mouse CD27 Ligand/CD70 Protein
    序列
    Ser45-Pro195
    产品特性
    Recombinant Mouse CD27 Ligand/CD70 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ser45-Pro195.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Mouse CD27, mFc Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Mouse CD27 Ligand, hFc Tag with the EC50 of 10.3ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product CD70 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 6.2). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    CD70 (CD70 Molecule (CD70))
    别名
    CD27 Ligand (CD70 产品)
    别名
    CD27LG Protein, Cd27l Protein, Tnfsf7 Protein, CD27L Protein, TNFSF7 Protein, CD70 antigen Protein, CD70 molecule Protein, Cd70 molecule Protein, Cd70 Protein, CD70 Protein
    背景
    CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
    分子量
    43.41 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.
    UniProt
    O55237
    途径
    Cancer Immune Checkpoints
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