CD70 Protein (AA 52-193) (His tag,AVI tag,DYKDDDDK Tag,Biotin)
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- 抗原 See all CD70 蛋白
- CD70 (CD70 Molecule (CD70))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 52-193
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD70 protein is labelled with His tag,AVI tag,DYKDDDDK Tag,Biotin.
- 序列
- AA 52-193
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CD70 蛋白
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CD70 Molecule (CD70) (AA 39-193) protein (Fc Tag)
CD70 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD70 Molecule (CD70) (AA 45-195) protein (Fc Tag)CD70 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD70 Molecule (CD70) (Trimer) protein (His tag)CD70 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
CD70 Molecule (CD70) (Trimer) protein (His tag,Biotin)CD70 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD70 Molecule (CD70) protein (mFc-His Tag)CD70 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD70 Molecule (CD70) (AA 39-194) protein (His tag)CD70 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,
CD70 Molecule (CD70) (AA 52-193) protein (His-DYKDDDDK-Strep II Tag)CD70 宿主: 人 宿主: HEK-293T Cells Recombinant SDS, WB, ELISA, PI
CD70 Molecule (CD70) (AA 52-193) (Active) protein (Fc Tag)CD70 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD70 Molecule (CD70) (AA 52-193) (Active) protein (DYKDDDDK Tag,His tag)CD70 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD70 Molecule (CD70) (AA 52-193) (Active) protein (His tag,DYKDDDDK Tag,FITC)CD70 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- 说明
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- CD70 (CD70 Molecule (CD70))
- 别名
- CD27 Ligand (CD70 产品)
- 别名
- CD27LG Protein, Cd27l Protein, Tnfsf7 Protein, CD27L Protein, TNFSF7 Protein, CD70 antigen Protein, CD70 molecule Protein, Cd70 molecule Protein, Cd70 Protein, CD70 Protein
- 背景
- Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells.
- 分子量
- 51.0 kDa
- NCBI登录号
- NP_001243
- 途径
- Cancer Immune Checkpoints
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