AXL Protein (AA 33-449) (His tag)
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- 抗原 See all AXL 蛋白
- AXL (AXL Receptor tyrosine Kinase (AXL))
- 蛋白类型
- Recombinant
- 产品特性
- AA 33-449
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宿主
- Cynomolgus
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资源
- HEK-293 Cells
- 标记
- This AXL protein is labelled with His tag.
- 原理
- Cynomolgus AXL Protein
- 序列
- Glu33-Pro449
- 产品特性
- Recombinant Cynomolgus AXL Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu33-Pro449.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus AXL, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-AXL Antibody, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA. The affinity constant of 1.70 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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- Discover our top product AXL 蛋白
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AXL Receptor tyrosine Kinase (AXL) (AA 33-442) protein (His tag)
AXL 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
AXL Receptor tyrosine Kinase (AXL) protein (His-Avi Tag)AXL 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by SEC-HPLC
AXL Receptor tyrosine Kinase (AXL) (AA 26-449) protein (Fc Tag)AXL 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
AXL Receptor tyrosine Kinase (AXL) protein (His-Avi Tag,Biotin)AXL 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
AXL Receptor tyrosine Kinase (AXL) (AA 26-449) protein (Fc Tag,Biotin)AXL 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
AXL Receptor tyrosine Kinase (AXL) (AA 473-894) protein (His tag)Crystallography grade AXL 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
AXL Receptor tyrosine Kinase (AXL) (AA 20-445) protein (His tag)AXL 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
AXL Receptor tyrosine Kinase (AXL) (AA 464-885) (Active) protein (GST tag)AXL 宿主: 人 宿主: Insect Cells Recombinant SDS, Func Active
AXL Receptor tyrosine Kinase (AXL) (AA 464-885) (Active) protein (His-GST)AXL 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
AXL Receptor tyrosine Kinase (AXL) (AA 1-894) protein (GST tag)AXL 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- AXL (AXL Receptor tyrosine Kinase (AXL))
- 别名
- AXL (AXL 产品)
- 别名
- JTK11 Protein, UFO Protein, AI323647 Protein, Ark Protein, Tyro7 Protein, Ufo Protein, AXL receptor tyrosine kinase Protein, Axl receptor tyrosine kinase Protein, AXL Protein, Axl Protein
- 背景
- Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.
- 分子量
- 46.3 kDa. Due to glycosylation, the protein migrates to 68-70 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A1D5Q330
- 途径
- RTK signaling, Cellular Response to Molecule of Bacterial Origin
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