Amphiregulin Protein (AREG) (AA 101-187) (Fc Tag)
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- 抗原 See all Amphiregulin (AREG) 蛋白
- Amphiregulin (AREG)
- 蛋白类型
- Recombinant
- 产品特性
- AA 101-187
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Amphiregulin protein is labelled with Fc Tag.
- 原理
- Human AREG Protein
- 序列
- Ser101-Lys187
- 产品特性
- Recombinant Human AREG Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ser101-Lys187.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human AREG, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-AREG Antibody, hFc Tag with the EC50 of 21.5ng/ml determined by ELISA. See testing image for detail.
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- Discover our top product AREG 蛋白
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Amphiregulin (AREG) (Active) protein
AREG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Amphiregulin (AREG) (AA 100-248) protein (Fc Tag)AREG 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Amphiregulin (AREG) (AA 101-198) protein (His tag)AREG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Amphiregulin (AREG) (AA 101-198) protein (His-IF2DI Tag)AREG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Amphiregulin (AREG) (AA 1-252) protein (GST tag)AREG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Amphiregulin (AREG) (AA 20-129) protein (GST tag)AREG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Amphiregulin (AREG)
- 别名
- AREG (AREG 产品)
- 别名
- AR Protein, CRDGF Protein, SDGF Protein, Sdgf Protein, AREG Protein, AREGB Protein, AREG/SDGF Protein, amphiregulin Protein, AREG Protein, Areg Protein
- 背景
- Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic cancer. AREG may play a critical role in cell migration, invasion, and EMT by activating the EGFR/ERK/NF-κB signalling pathway in pancreatic cancer cells.
- 分子量
- 37.3 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result.
- UniProt
- P15514
- 途径
- RTK signaling, EGFR Signaling Pathway
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