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Amphiregulin Protein (AREG) (AA 101-198)

AREG 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1692249
发货至: 中国
  • 抗原 See all Amphiregulin (AREG) 蛋白
    Amphiregulin (AREG)
    蛋白类型
    Recombinant
    产品特性
    AA 101-198
    宿主
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    资源
    • 16
    • 2
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Human Amphiregulin/AREG
    序列
    MSVRVEQVVK PPQNKTESEN TSDKPKRKKK GGKNGKNRRN RKKKNPCNAE FQNFCIHGEC KYIEHLEAVT CKCQQEYFGE RCGEKSMKTH SMIDSSLSK
    产品特性

    Recombinant Human Amphiregulin/AREG

    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product AREG 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    4 °C/-20 °C/-80 °C
    储存方法
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Amphiregulin (AREG)
    别名
    Amphiregulin/AREG (AREG 产品)
    别名
    AR Protein, CRDGF Protein, SDGF Protein, Sdgf Protein, AREG Protein, AREGB Protein, AREG/SDGF Protein, amphiregulin Protein, AREG Protein, Areg Protein
    背景
    Recombinant Human Amphiregulin/AREG is produced with our E. coli expression system. The target protein is expressed with sequence (Ser101-Lys198) of Human AREG.
    Amphiregulin (AREG) is a single-pass membrane protein with 252 AAs. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor α (TGF-α). As an EGF-related growth factor, AREG interacts with the EGF/TGF-α receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy.
    分子量
    11.4 kDa
    UniProt
    P15514
    途径
    RTK signaling, EGFR Signaling Pathway
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