FOLR1 Protein (Biotin,His-Avi Tag)
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- 抗原 See all FOLR1 蛋白
- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This FOLR1 protein is labelled with Biotin,His-Avi Tag.
- 原理
- Recombinant Human Folate Receptor alpha/FOLR1 (C-6His-Avi) Biotinylated
- 序列
- Arg25-Ser234
- 产品特性
- Biotinylated Recombinant Human Folate Receptor Alpha is produced by our Mammalian expression system and the target gene encoding Arg25-Ser234 is expressed with a 6His, Avi tag at the C-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product FOLR1 蛋白
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Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) protein (His-Avi Tag)
FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) protein (Fc Tag)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) protein (His tag)FOLR1 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) protein (His-Avi Tag,Biotin)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) (AA 25-232) protein (His tag)FOLR1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) (Active) protein (His tag)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) (Active) protein (His tag)FOLR1 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) (Active) protein (Fc Tag,AVI tag,Biotin)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) (Active) protein (His tag,AVI tag,Biotin)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) protein (Strep Tag)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- 说明
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35-40 kDa
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
- 别名
- FOLR1 (FOLR1 产品)
- 别名
- FBP Protein, FOLR Protein, fbp Protein, folr Protein, folr1 Protein, FBP1 Protein, Folbp-1 Protein, Folbp1 Protein, Fbp1 Protein, FOLR1 Protein, Folr1 Protein, folate receptor 1 Protein, folate receptor 1 (adult) Protein, folate receptor 1 (adult) L homeolog Protein, zgc:165502 Protein, Folate receptor alpha Protein, folate receptor alpha Protein, FOLR1 Protein, folr1 Protein, folr1.L Protein, zgc:165502 Protein, Folr1 Protein, LOC100066084 Protein, LOC100725439 Protein
- 背景
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Background: Folate receptor alpha(FOLR) belongs to the folate receptor family, and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney, lung and cerebellum. The secreted form is derived from the membrane-bound form either by cleavage of the GPI anchor, or/and by proteolysis catalyzed by a metalloprotease. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. It has high affinity for folate and folic acid analogs at neutral pH . Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. It is required for normal embryonic development and normal cell proliferation.
Synonym: Folate receptor alpha, FR-alpha, Adult folate-binding protein, FBP, Folate receptor 1, Folate receptor, Ovarian tumor-associated antigen MOv18, FOLR1
- 分子量
- 27.5 kDa
- UniProt
- P15328
- 途径
- Dicarboxylic Acid Transport
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