FOLR1 Protein (AA 25-233) (Fc Tag,AVI tag,Biotin)
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- 抗原 See all FOLR1 蛋白
- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 25-233
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FOLR1 protein is labelled with Fc Tag,AVI tag,Biotin.
- 序列
- AA 25-233
- 特异性
- Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product FOLR1 蛋白
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Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) protein (His-Avi Tag)
FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) protein (Fc Tag)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) protein (His tag)FOLR1 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) protein (His-Avi Tag,Biotin)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) (AA 25-232) protein (His tag)FOLR1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) (Active) protein (His tag)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) (Active) protein (His tag)FOLR1 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) (Active) protein (His tag,AVI tag,Biotin)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Folate Receptor 1 (Adult) (FOLR1) (AA 25-233) protein (Strep Tag)FOLR1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Folate Receptor 1 (Adult) (FOLR1) protein (Fc Tag)FOLR1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
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- 说明
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Ready-to-use AvitagTM biotinylated protein:
The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.
This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled. - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
- 别名
- FOLR1 (FOLR1 产品)
- 别名
- FBP Protein, FOLR Protein, fbp Protein, folr Protein, folr1 Protein, FBP1 Protein, Folbp-1 Protein, Folbp1 Protein, Fbp1 Protein, FOLR1 Protein, Folr1 Protein, folate receptor 1 Protein, folate receptor 1 (adult) Protein, folate receptor 1 (adult) L homeolog Protein, zgc:165502 Protein, Folate receptor alpha Protein, folate receptor alpha Protein, FOLR1 Protein, folr1 Protein, folr1.L Protein, zgc:165502 Protein, Folr1 Protein, LOC100066084 Protein, LOC100725439 Protein
- 背景
- Folate Receptor 1 (FOLR1) is also known as Folate receptor alpha, Folate Binding Protein (FBP), FOLR, and is a member of the folate receptor (FOLR) family. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Mature FOLR1 is an N-glycosylated protein that is anchored to the cell surface by a GPI linkage. FOLR1 is predominantly expressed on epithelial cells and is dramatically upregulated on many carcinomas. FOLR1 is internalized to the endosomal system where it dissociates from its ligand before recycling to the cell surface. A soluble form of FOLR1 can be proteolytically shed from the cell surface into the serum and breast milk. Defects in FOLR1 are the cause of neurodegeneration due to cerebral folate transport deficiency (NCFTD). NCFTD is an autosomal recessive disorder resulting from brain-specific folate deficiency early in life.
- 分子量
- 53.3 kDa
- NCBI登录号
- NP_057937
- 途径
- Dicarboxylic Acid Transport
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