TNFSF14 Protein (mFc Tag)
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- 抗原 See all TNFSF14 蛋白
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This TNFSF14 protein is labelled with mFc Tag.
- 原理
- Recombinant Human TNFSF14/LIGHT Protein (mFc Tag)
- 序列
- Ile84-Val240(Lys214Glu)
- 产品特性
- Recombinant Human LIGHT is produced by our Mammalian expression system and the target gene encoding Ile84-Val240(Lys214Glu) is expressed with a mFc tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TNFSF14 蛋白
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Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (Trimer) protein (His-DYKDDDDK Tag)
TNFSF14 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 74-240) protein (His tag)TNFSF14 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 74-240) protein (Fc Tag)TNFSF14 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 89-240) protein (His-DYKDDDDK-Strep II Tag)TNFSF14 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 74-240) (Active) protein (His tag)TNFSF14 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 71-240) protein (His-IF2DI Tag)TNFSF14 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-177) protein (GST tag)TNFSF14 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-204) protein (GST tag)TNFSF14 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 61-170) protein (GST tag)TNFSF14 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- 别名
- TNFSF14/LIGHT (TNFSF14 产品)
- 别名
- TNFSF14 Protein, CD258 Protein, HVEML Protein, LIGHT Protein, LTg Protein, TR2 Protein, HVEM-L Protein, Ly113 Protein, TNF superfamily member 14 Protein, tumor necrosis factor (ligand) superfamily, member 14 Protein, TNFSF14 Protein, Tnfsf14 Protein
- 背景
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Background: Human TNFSF14 Protein, also known as LIGHT, belongs to a member of the tumor necrosis factor (TNF) ligand family. It can bind to NFRSF3/LTBR. It is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and it is also known as a herpesvirus entry mediator ligand (HVEML). TNFSF14 encodes a protein with a 37 aa cytoplasmic domain, 21aa transmembrane domain and 182 aa extracellular region. The gene is predominantly expressed in the spleen and also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines. TNFSF14 protein was found to probably function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. Studies have shown that this protein can prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.
Synonym: CD258,HVEML,LIGHT,LTg,TR2,Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, TNFSF14, HVEM-L, LIGHT
- 分子量
- 43.3 kDa
- UniProt
- O43557
- 途径
- Cancer Immune Checkpoints
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