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SDC4 Protein (AA 24-145) (His tag)

SDC4 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320707
发货至: 中国
  • 抗原 See all SDC4 蛋白
    SDC4 (Syndecan 4 (SDC4))
    蛋白类型
    Recombinant
    产品特性
    AA 24-145
    宿主
    • 10
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    小鼠
    资源
    • 8
    • 6
    • 4
    • 3
    • 2
    人细胞
    标记
    This SDC4 protein is labelled with His tag.
    原理
    Recombinant Mouse Syndecan-4/SDC4 Protein (aa 24-145, His Tag)
    序列
    Glu24-Glu145
    产品特性
    Recombinant Mouse Syndecan-4 is produced by our Mammalian expression system and the target gene encoding Glu24-Glu145 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SDC4 (Syndecan 4 (SDC4))
    别名
    Syndecan-4/SDC4 (SDC4 产品)
    别名
    SYND4 Protein, AA959608 Protein, AW108331 Protein, Synd4 Protein, ryudocan Protein, syndecan-4 Protein, RATRYUDOCA Protein, RYUDOCA Protein, SDC4 Protein, sdc4l Protein, wu:fc47g09 Protein, Syndecan-4 Protein, amphiglycan Protein, syn-4 Protein, syn4 Protein, syndecan 4 Protein, syndecan 4 S homeolog Protein, syndecan 4 L homeolog Protein, SDC4 Protein, Sdc4 Protein, sdc4 Protein, sdc4.S Protein, sdc4.L Protein
    背景

    Background: Mouse SDC4 is a ubiquitous transmembrane proteoglycan which belongs to the syndecan proteoglycan family. SDC4 is a cell surface proteoglycan that bears heparan sulfate. The four vertebrate syndecans, Syndecan-1 through -4, have similar short cytoplasmic domains and extracellular portions that diverge, except for HS attachment sites. Structurally diverse side chains add considerably to the size of the core proteins and serve as binding sites for growth factors, cytokines, and extracellular matrix proteins. Syndecans are present as homodimers or multimers, and are often expressed in developmental and cell type-specific patterns. It is expressed highly in liver, kidney and lung. SDC4 localizes to the focal adhesions of adherent cells and binds to a range of extracellular ligands, including growth factors and extracellular-matrix proteins. Through its extracellular domain, syndecan-4 cooperates with adhesion molecules and binds matrix components relevant for cell migration. As a heparan sulfate proteoglycan, SDC4 works as a coreceptor for various growth factors. Syn4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cells (VSMCs) proliferation and vascular progenitor cells (VPCs) mobilization. SDC4 have an array of functions including regulating cell growth, differentiation, and adhesion.

    Synonym: AA959608,AW108331,ryudocan,Synd4,syndecan-4,SDC4,SYND4,Ryudocan core protein

    分子量
    14.4 kDa
    UniProt
    O35988
    途径
    Glycosaminoglycan Metabolic Process
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