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SDC4 Protein (AA 1-146) (His tag)

SDC4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320170
发货至: 中国
  • 抗原 See all SDC4 蛋白
    SDC4 (Syndecan 4 (SDC4))
    蛋白类型
    Recombinant
    产品特性
    AA 1-146
    宿主
    • 10
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    小鼠
    资源
    • 8
    • 6
    • 4
    • 3
    • 1
    • 1
    HEK-293 Cells
    标记
    This SDC4 protein is labelled with His tag.
    原理
    Recombinant Mouse Syndecan-4/SDC4 Protein (aa 1-146, His Tag)
    序列
    Met 1-Val 146
    产品特性
    A DNA sequence encoding the mouse SDC4 (O35988) extracellular domain (Met 1-Val 146) was expressed, fused with a C-terminal polyhistidine tag.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product SDC4 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SDC4 (Syndecan 4 (SDC4))
    别名
    Syndecan-4/SDC4 (SDC4 产品)
    别名
    SYND4 Protein, AA959608 Protein, AW108331 Protein, Synd4 Protein, ryudocan Protein, syndecan-4 Protein, RATRYUDOCA Protein, RYUDOCA Protein, SDC4 Protein, sdc4l Protein, wu:fc47g09 Protein, Syndecan-4 Protein, amphiglycan Protein, syn-4 Protein, syn4 Protein, syndecan 4 Protein, syndecan 4 S homeolog Protein, syndecan 4 L homeolog Protein, SDC4 Protein, Sdc4 Protein, sdc4 Protein, sdc4.S Protein, sdc4.L Protein
    背景

    Background: SDC4 (Syndecan-4), also known as Syn4, is a transmembrane heparan sulfate proteoglycan that co-operates with integrins during cell-matrix interactions for the assembly of focal adhesions and actin stress fibers and in the phosphorylation of focal adhesion kinase (FAK) on Tyr397. Syndecan-4 plays roles in the formation of focal adhesions and stress fibers. The cytoplasmic domain of syndecan-4 interacts with a number of signalling and structural proteins, and both extracellular and cytoplasmic domains are necessary for regulated activation of associated transmembrane receptors. Syndecan-4/SDC4 is a heparan sulfate proteoglycan and works as a coreceptor for various growth factors. SDC4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cells (VSMCs) proliferation and vascular progenitor cells (VPCs) mobilization. Therefore, SDC4 may be a novel therapeutic target for preventing arterial restenosis after angioplasty.

    Synonym: AA959608,AW108331,ryudocan,Synd4,syndecan-4,SDC4,SYND4,Ryudocan core protein

    分子量
    14.9 kDa
    UniProt
    O35988
    途径
    Glycosaminoglycan Metabolic Process
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