SDC4 Protein (Fc Tag)
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- 抗原 See all SDC4 蛋白
- SDC4 (Syndecan 4 (SDC4))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This SDC4 protein is labelled with Fc Tag.
- 原理
- Recombinant Mouse Syndecan-4/SDC4 Protein (Fc Tag)(Active)
- 序列
- Met1-Val146
- 产品特性
- A DNA sequence encoding the mouse SDC4 (O35988)(Met1-Val146) was expressed with the Fc region of human IgG1 at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized human MDK at 10 μg/ml (100 μl/well) can bind mouse SDC4-Fc with a linear range of 0.16-1.25 μg/ml.
- Top Product
- Discover our top product SDC4 蛋白
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Syndecan 4 (SDC4) (AA 24-145) protein (His tag)
SDC4 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Syndecan 4 (SDC4) (AA 19-198) protein (GST tag)SDC4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Syndecan 4 (SDC4) (AA 1-198) protein (GST tag)SDC4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Syndecan 4 (SDC4) (AA 31-130) protein (GST tag)SDC4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Syndecan 4 (SDC4) (AA 19-145) proteinSDC4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % by SDS - PAGE SDS
Syndecan 4 (SDC4) (AA 1-146) protein (His tag)SDC4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Syndecan 4 (SDC4) (AA 19-145) protein (His tag)Crystallography grade SDC4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Syndecan 4 (SDC4) (AA 24-145) protein (His tag)Crystallography grade SDC4 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Syndecan 4 (SDC4) (AA 19-198) protein (rho-1D4 tag)Crystallography grade SDC4 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Syndecan 4 (SDC4) (AA 24-198) protein (rho-1D4 tag)Crystallography grade SDC4 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SDC4 (Syndecan 4 (SDC4))
- 别名
- Syndecan-4/SDC4 (SDC4 产品)
- 别名
- SYND4 Protein, AA959608 Protein, AW108331 Protein, Synd4 Protein, ryudocan Protein, syndecan-4 Protein, RATRYUDOCA Protein, RYUDOCA Protein, SDC4 Protein, sdc4l Protein, wu:fc47g09 Protein, Syndecan-4 Protein, amphiglycan Protein, syn-4 Protein, syn4 Protein, syndecan 4 Protein, syndecan 4 S homeolog Protein, syndecan 4 L homeolog Protein, SDC4 Protein, Sdc4 Protein, sdc4 Protein, sdc4.S Protein, sdc4.L Protein
- 背景
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Background: SDC4 (Syndecan-4), also known as Syn4, is a transmembrane heparan sulfate proteoglycan that co-operates with integrins during cell-matrix interactions for the assembly of focal adhesions and actin stress fibers and in the phosphorylation of focal adhesion kinase (FAK) on Tyr397. Syndecan-4 plays roles in the formation of focal adhesions and stress fibers. The cytoplasmic domain of syndecan-4 interacts with a number of signalling and structural proteins, and both extracellular and cytoplasmic domains are necessary for regulated activation of associated transmembrane receptors. Syndecan-4/SDC4 is a heparan sulfate proteoglycan and works as a coreceptor for various growth factors. SDC4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cells (VSMCs) proliferation and vascular progenitor cells (VPCs) mobilization. Therefore, SDC4 may be a novel therapeutic target for preventing arterial restenosis after angioplasty.
Synonym: AA959608,AW108331,ryudocan,Synd4,syndecan-4,SDC4,SYND4,Ryudocan core protein
- 分子量
- 40.5 kDa
- UniProt
- O35988
- 途径
- Glycosaminoglycan Metabolic Process
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