SMPDL3A Protein (His tag)
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- 抗原 See all SMPDL3A 蛋白
- SMPDL3A (Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This SMPDL3A protein is labelled with His tag.
- 原理
- Recombinant Mouse SMPDL3A Protein (His Tag)
- 序列
- Met1-Leu445
- 产品特性
- A DNA sequence encoding the mouse Smpdl3a (NP_065586.3) (Met1-Leu445) was expressed with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product SMPDL3A 蛋白
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Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A) (AA 1-453) protein (GST tag)
SMPDL3A 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A) (AA 23-445) protein (His tag)Crystallography grade SMPDL3A 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A) (AA 23-453) protein (His tag)Crystallography grade SMPDL3A 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SMPDL3A (Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A))
- 别名
- SMPDL3A (SMPDL3A 产品)
- 别名
- ASM3A Protein, ASML3a Protein, yR36GH4.1 Protein, 0610010C24Rik Protein, AI529588 Protein, ASML3 Protein, ASML3A Protein, sphingomyelin phosphodiesterase acid like 3A Protein, sphingomyelin phosphodiesterase, acid-like 3A Protein, SMPDL3A Protein, Smpdl3a Protein
- 背景
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Background: SMPDL3A gene is a novel liver X receptor (LXR) -regulated gene, with an LXR response element within its promoter. The induction of SMPDL3A is LXR-dependent and is restricted to human blood cells with no induction observed in mouse cellular systems. LXR α and LXRβ function as physiological sensors of cholesterol metabolites (oxysterols), regulating key genes involved in cholesterol and lipid metabolism. LXRs have been extensively studied in both human and rodent cell systems, revealing their potential therapeutic value in the contexts of atherosclerosis and inflammatory diseases. The LXR genome landscape has been investigated in murine macrophages but not in human THP-1 cells, which represent one of the frequently used monocyte/macrophage cell systems to study immune responses.
Synonym: 0610010C24Rik,AI529588,ASM3A,ASML3,ASML3A
- 分子量
- 49.1 kDa
- NCBI登录号
- NP_065586
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