SMPDL3A Protein (AA 23-453) (His tag)
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- 抗原 See all SMPDL3A 蛋白
- SMPDL3A (Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A))
- 蛋白类型
- Recombinant
- 产品特性
- AA 23-453
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宿主
- 人
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资源
- 人细胞
- 标记
- This SMPDL3A protein is labelled with His tag.
- 原理
- Recombinant Human ASM-Like Phosphodiesterase 3a/SMPDL3A (C-6His)
- 序列
- LPVAPAGGRN PPPAIGQFWH VTDLHLDPTY HITDDHTKVC ASSKGANASN PGPFGDVLCD SPYQLILSAF DFIKNSGQEA SFMIWTGDSP PHVPVPELST DTVINVITNM TTTIQSLFPN LQVFPALGNH DYWPQDQLPV VTSKVYNAVA NLWKPWLDEE AISTLRKGGF YSQKVTTNPN LRIISLNTNL YYGPNIMTLN KTDPANQFEW LESTLNNSQQ NKEKVYIIAH VPVGYLPSSQ NITAMREYYN EKLIDIFQKY SDVIAGQFYG HTHRDSIMVL SDKKGSPVNS LFVAPAVTPV KSVLEKQTNN PGIRLFQYDP RDYKLLDMLQ YYLNLTEANL KGESIWKLEY ILTQTYDIED LQPESLYGLA KQFTILDSKQ FIKYYNYFFV SYDSSVTCDK TCKAFQICAI MNLDNISYAD CLKQLYIKHN YVDHHHHHH
- 产品特性
- Recombinant Human Acid sphingomyelinase-like phosphodiesterase 3a/SMPDL3A is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Leu23-Tyr453) of Human SMPDL3A fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 过滤
- 0.2 μm filtered
- 内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product SMPDL3A 蛋白
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Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A) (AA 1-453) protein (GST tag)
SMPDL3A 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A) protein (His tag)SMPDL3A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A) (AA 23-445) protein (His tag)Crystallography grade SMPDL3A 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A) (AA 23-453) protein (His tag)Crystallography grade SMPDL3A 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- 储存条件
- 4 °C/-20 °C/-80 °C
- 储存方法
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - 有效期
- 5 months
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- 抗原
- SMPDL3A (Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A))
- 别名
- SMPDL3A (SMPDL3A 产品)
- 别名
- ASM3A Protein, ASML3a Protein, yR36GH4.1 Protein, 0610010C24Rik Protein, AI529588 Protein, ASML3 Protein, ASML3A Protein, sphingomyelin phosphodiesterase acid like 3A Protein, sphingomyelin phosphodiesterase, acid-like 3A Protein, SMPDL3A Protein, Smpdl3a Protein
- Sub Type
- Fusionprotein
- 背景
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Acid sphingomyelinase-like phosphodiesterase 3a (SMPDL3A ) is a novel liver X receptor (LXR) -regulated gene, with an LXR response element within its promoter. The induction of SMPDL3A is LXR-dependent and is restricted to human blood cells with no induction observed in mouse cellular systems. LXR and LXR function as physiological sensors of cholesterol metabolites (oxysterols), regulating key genes involved in cholesterol and lipid metabolism. LXRs have been extensively studied in both human and rodent cell systems, revealing their potential therapeutic value in the contexts of atherosclerosis and inflammatory diseases. The LXR genome landscape has been investigated in murine macrophages but not in human THP-1 cells, which represent one of the frequently used monocyte/macrophage cell systems to study immune responses.
Alternative Names: - 分子量
- 49.9 kDa
- UniProt
- Q92484
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