SMPDL3A Protein (His tag)
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- 抗原 See all SMPDL3A 蛋白
- SMPDL3A (Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This SMPDL3A protein is labelled with His tag.
- 原理
- Recombinant Human SMPDL3A Protein (His Tag)
- 序列
- Leu23-Tyr453
- 产品特性
- Recombinant Human Acid sphingomyelinase-like phosphodiesterase 3a is produced by our Mammalian expression system and the target gene encoding Leu23-Tyr453 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SMPDL3A 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SMPDL3A (Sphingomyelin phosphodiesterase, Acid-Like 3A (SMPDL3A))
- 别名
- SMPDL3A (SMPDL3A 产品)
- 别名
- ASM3A Protein, ASML3a Protein, yR36GH4.1 Protein, 0610010C24Rik Protein, AI529588 Protein, ASML3 Protein, ASML3A Protein, sphingomyelin phosphodiesterase acid like 3A Protein, sphingomyelin phosphodiesterase, acid-like 3A Protein, SMPDL3A Protein, Smpdl3a Protein
- 背景
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Background: Acid sphingomyelinase-like phosphodiesterase 3a (SMPDL3A ) is a novel liver X receptor (LXR) -regulated gene, with an LXR response element within its promoter. The induction of SMPDL3A is LXR-dependent and is restricted to human blood cells with no induction observed in mouse cellular systems. LXR function as physiological sensors of cholesterol metabolites (oxysterols), regulating key genes involved in cholesterol and lipid metabolism. LXRs have been extensively studied in both human and rodent cell systems, revealing their potential therapeutic value in the contexts of atherosclerosis and inflammatory diseases.
Synonym: Acid Sphingomyelinase-Like Phosphodiesterase 3a, ASM-Like Phosphodiesterase 3a,SMPDL3A,ASML3A
- 分子量
- 49.9 kDa
- UniProt
- Q92484
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