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SERPINA7 Protein (His tag)

SERPINA7 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE
产品编号 ABIN7197956
发货至: 中国
  • 抗原 See all SERPINA7 蛋白
    SERPINA7 (Serpin Family A Member 7 (SERPINA7))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    小鼠
    资源
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    标记
    This SERPINA7 protein is labelled with His tag.
    原理
    Recombinant Mouse SerpinA7/TBG Protein (His Tag)
    序列
    Met 1-Gln 418
    产品特性
    A DNA sequence encoding the mouse SERPINA7 (NP_808588.3) (Met 1-Gln 418) was fused with a polyhistidine tag at the C-terminus.
    纯度
    > 97 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product SERPINA7 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SERPINA7 (Serpin Family A Member 7 (SERPINA7))
    别名
    SerpinA7/TBG (SERPINA7 产品)
    别名
    C730040N12Rik Protein, Tbg Protein, TBG Protein, THYROXINE-BINDING GLOBULIN Protein, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 Protein, serpin family A member 7 Protein, Serpina7 Protein, SERPINA7 Protein
    背景

    Background: Thyroxine-binding globulin, also known as T4-binding globulin, Serpin A7 and TBG, is a secreted protein which belongs to the serpin family. TBG is synthesized primarily in the liver as a 54 kDa protein.TBG is genomically a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG binds thyroid hormone in circulation. It is one of three proteins (along with transthyretin and albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 and T3, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. TBG tests are sometimes used in finding the reason for elevated or diminished levels of thyroid hormone.

    Synonym: C730040N12Rik;Tbg

    分子量
    46.2 kDa
    NCBI登录号
    NP_808588
    途径
    Hormone Transport
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