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SERPINA7 Protein (His tag)

SERPINA7 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319792
发货至: 中国
  • 抗原 See all SERPINA7 蛋白
    SERPINA7 (Serpin Family A Member 7 (SERPINA7))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    资源
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    人细胞
    标记
    This SERPINA7 protein is labelled with His tag.
    原理
    Recombinant Human Serpin A7/TBG (C-6His)
    序列
    Ala21-Ala415
    产品特性
    Recombinant Human Serine Protease Inhibitor-clade A7 is produced by our Mammalian expression system and the target gene encoding Ala21-Ala415 is expressed with a 6His tag at the C-terminus.
    纯度
    >95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product SERPINA7 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SERPINA7 (Serpin Family A Member 7 (SERPINA7))
    别名
    Serpin A7/TBG (SERPINA7 产品)
    别名
    C730040N12Rik Protein, Tbg Protein, TBG Protein, THYROXINE-BINDING GLOBULIN Protein, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 Protein, serpin family A member 7 Protein, Serpina7 Protein, SERPINA7 Protein
    背景

    Background: Serpin A7 is a secreted protein which belongs to the Serpin family. As a 54 kDa protein, Serpin A7 is synthesized primarily in the liver and secreted in plasma. Genomically, Serpin A7 is a serpin, although it has no inhibitory function like many other members of this class of proteins. Serpin A7 binds thyroid hormone in circulation. It is one of three proteins (along with transthyretin and albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. Of these three proteins, Serpin A7 has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, Serpin A7 carries the majority of T4 in serum. Due to the very low serum concentration of T4 and T3 in the blood, Serpin A7 is rarely more than 25 % saturated with its ligand. Unlike transthyretin and albumin, Serpin A7 has a single binding site for T4/T3. Serpin A7 tests are sometimes used in finding the reason for elevated or diminished levels of thyroid hormone, and defects in Serpin A7 are a cause of Serpin A7 deficiency.

    Synonym: Thyroxine-Binding Globulin, Serpin A7, T4-Binding Globulin, SERPINA7, TBG

    分子量
    49.9 kDa
    UniProt
    P05543
    途径
    Hormone Transport
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