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SCARB2 Protein (His tag,Fc Tag)

SCARB2 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7317675
发货至: 中国
  • 抗原 See all SCARB2 蛋白
    SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 12
    • 6
    资源
    • 6
    • 6
    • 4
    • 2
    HEK-293 Cells
    标记
    This SCARB2 protein is labelled with His tag,Fc Tag.
    原理
    Recombinant Human LIMP-2/LIMPII Protein (His & Fc Tag)(Active)
    序列
    Arg 27-Thr 432
    产品特性
    A DNA sequence encoding the human SCARB2 (NP_005497.1) extracellular domain (Arg 27-Thr 432) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to bind recombinant human RSPO1 in a functional ELISA.
    Top Product
    Discover our top product SCARB2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
    别名
    LIMP-2/LIMPII (SCARB2 产品)
    别名
    cd36l2 Protein, fi13c07 Protein, chunp6914 Protein, wu:fi13c07 Protein, SCARB2 Protein, scarb2 Protein, AMRF Protein, CD36L2 Protein, EPM4 Protein, HLGP85 Protein, LGP85 Protein, LIMP-2 Protein, LIMPII Protein, SR-BII Protein, 9330185J12Rik Protein, Cd36l2 Protein, MLGP85 Protein, LimpII Protein, scavenger receptor class B, member 2a Protein, scavenger receptor class B member 2 Protein, scavenger receptor class B, member 2 Protein, scarb2a Protein, SCARB2 Protein, scarb2 Protein, Scarb2 Protein
    背景

    Background: Lysosomal Integral Membrane Protein II (LIMPII), also known as SCARB2, LPG85, and CD36L2, is a type I II multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. This protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. LIMPII is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Expression of human LIMPII enables normally unsusceptible cell lines to support the viruses' propagation and develop cytopathic effects. In addition, LIMPII also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation. Deficiency of the protein in mice impairs cell membrane transport processes and causes pelvic junction obstruction, deafness, and peripheral neuropathy.

    Synonym: Lysosome Membrane Protein 2; 85 kDa Lysosomal Membrane Sialoglycoprotein; LGP85; CD36 Antigen-Like 2; Lysosome Membrane Protein II; LIMP II; Scavenger Receptor Class B Member 2; CD36; SCARB2; CD36L2; LIMPII;AMRF;CD36L2;EPM4;HLGP85;LGP85;SR-BII

    分子量
    74.4 kDa
    NCBI登录号
    NP_005497
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