SCARB2 Protein (His tag)
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- 抗原 See all SCARB2 蛋白
- SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This SCARB2 protein is labelled with His tag.
- 原理
- Recombinant Human LIMP-2/LIMPII Protein (His Tag)
- 序列
- Arg27-Thr432
- 产品特性
- Recombinant Human LIMP-2 is produced by our Mammalian expression system and the target gene encoding Arg27-Thr432 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SCARB2 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
- 别名
- LIMP-2/LIMPII (SCARB2 产品)
- 别名
- cd36l2 Protein, fi13c07 Protein, chunp6914 Protein, wu:fi13c07 Protein, SCARB2 Protein, scarb2 Protein, AMRF Protein, CD36L2 Protein, EPM4 Protein, HLGP85 Protein, LGP85 Protein, LIMP-2 Protein, LIMPII Protein, SR-BII Protein, 9330185J12Rik Protein, Cd36l2 Protein, MLGP85 Protein, LimpII Protein, scavenger receptor class B, member 2a Protein, scavenger receptor class B member 2 Protein, scavenger receptor class B, member 2 Protein, scarb2a Protein, SCARB2 Protein, scarb2 Protein, Scarb2 Protein
- 背景
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Background: Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. In addition, SCARB2 also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation.
Synonym: Lysosome Membrane Protein 2, 85 kDa Lysosomal Membrane Sialoglycoprotein, LGP85, CD36 Antigen-Like 2, Lysosome Membrane Protein II, LIMP II, Scavenger Receptor Class B Member 2, CD36, SCARB2, CD36L2, LIMPII,AMRF,CD36L2,EPM4,HLGP85,LGP85,SR-BII
- 分子量
- 47.59 kDa
- UniProt
- Q14108
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