SCARB2 产品
(Scavenger Receptor Class B, Member 2 (SCARB2))
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The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011].
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Featured SCARB2 Categories
SCARB2 抗体
High quality antibodies with extensive validation data.
SCARB2 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
SCARB2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended SCARB2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7158800
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (3)
Cat. No.
ABIN873185
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN560246
Quantity
50 μL
Datasheet
Datasheet
Recommended SCARB2 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN2703297
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1141296
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1141297
Quantity
96 tests
Datasheet
Datasheet
Recommended SCARB2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7320637
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7320638
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1319219
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our SCARB2 Products
: "Endophilin-A2-mediated endocytic pathway is critical for enterovirus 71 entry into caco-2 cells." in: Emerging microbes & infections, Vol. 8, Issue 1, pp. 773-786, (2019) (PubMed).: "Intra-host emergence of an enterovirus A71 variant with enhanced PSGL1 usage and neurovirulence." in: Emerging microbes & infections, Vol. 8, Issue 1, pp. 1076-1085, (2019) (PubMed).
: "Age-related endolysosome dysfunction in the rat urothelium." in: PLoS ONE, Vol. 13, Issue 6, pp. e0198817, (2018) (PubMed).
: "Glutamine-dependent lysosome homeostatic changes induced by starvation and lysosome inhibition." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1865, Issue 9, pp. 1356-1367, (2018) (PubMed).
: "Evaluation of AAV-mediated Gene Therapy for Central Nervous System Disease in Canine Mucopolysaccharidosis VII." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 24, Issue 2, pp. 206-16, (2016) (PubMed).
: "Progressive neurologic and somatic disease in a novel mouse model of human mucopolysaccharidosis type IIIC." in: Disease models & mechanisms, Vol. 9, Issue 9, pp. 999-1013, (2016) (PubMed).
: "A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71." in: Scientific reports, Vol. 6, pp. 31151, (2016) (PubMed).
: "Mutation in VPS33A affects metabolism of glycosaminoglycans: a new type of mucopolysaccharidosis with severe systemic symptoms." in: Human molecular genetics, Vol. 26, Issue 1, pp. 173-183, (2016) (PubMed).
: "Liver growth factor induces testicular regeneration in EDS-treated rats and increases protein levels of class B scavenger receptors." in: American journal of physiology. Endocrinology and metabolism, Vol. 308, Issue 2, pp. E111-21, (2015) (PubMed).
: "Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis." in: Cellular and molecular gastroenterology and hepatology, Vol. 1, Issue 6, pp. 678-694, (2015) (PubMed).
Synonyms and alternative names related to SCARB2
scavenger receptor class B, member 2a (scarb2a), scavenger receptor class B member 2 (SCARB2), scavenger receptor class B member 2 (scarb2), scavenger receptor class B, member 2 (Scarb2), 9330185J12Rik, AMRF, cd36l2, CD36L2, Cd36l2, chunp6914, EPM4, fi13c07, HLGP85, LGP85, LIMP-2, LIMPII, LimpII, MLGP85, SCARB2, scarb2, SR-BII, wu:fi13c07Protein level used designations for SCARB2
- CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2
- CD36 antigen-like 2
- lysosome membrane protein 2
- scavenger receptor class B, member 2
- lysosome membrane protein 2-like
- putative lysosomal integral membrane protein II
- 85 kDa lysosomal membrane sialoglycoprotein
- 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2
- CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II)
- LIMP II
- lysosome membrane protein II
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