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ROR1 Protein (His tag,ECD)

ROR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7197643
发货至: 中国
  • 抗原 See all ROR1 蛋白
    ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
    蛋白类型
    Recombinant
    宿主
    • 33
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    • 8
    • 8
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    • 1
    • 1
    资源
    • 26
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    HEK-293 Cells
    标记
    This ROR1 protein is labelled with His tag,ECD.
    原理
    Recombinant Human ROR1 Protein (ECD, His Tag)
    序列
    Met 1-Glu403
    产品特性
    A DNA sequence encoding the human ROR1 (NP_005003.2) (Met1-Glu403) was expressed with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product ROR1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))
    别名
    ROR1 (ROR1 产品)
    别名
    NTRKR1 Protein, dJ537F10.1 Protein, 2810404D04Rik Protein, Ntrkr1 Protein, mRor1 Protein, RGD1559469 Protein, ROR1 Protein, fi34e02 Protein, si:dkey-209n16.1 Protein, wu:fi34e02 Protein, receptor tyrosine kinase like orphan receptor 1 Protein, receptor tyrosine kinase-like orphan receptor 1 Protein, ROR1 Protein, Ror1 Protein, ror1 Protein
    背景

    Background: Receptor tyrosine kinase-like orphan receptor 1 (ROR1), also known as neurotrophic tyrosine kinase, it is a member of the ROR family within receptor tyrosine kinases (RTK) superfamily. Human ROR1 is a type I transmembrane protein with 937 amino acids (aa) in length. It contains a 29 aa signal sequence, a 377 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 510 aa cytoplasmic region. ROR1 expressed strongly in human heart, lung and kidney, but weakly in the CNS. At developmental stage, it expressed at high levels during early embryonic development. ROR1 has been shown to have very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. It may act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling.

    Synonym: dJ537F10.1,NTRKR1

    分子量
    43.4 kDa
    NCBI登录号
    NP_005003
    途径
    RTK signaling, WNT signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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