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RHEB Protein (GST tag)

RHEB 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319480
发货至: 中国
  • 抗原 See all RHEB 蛋白
    RHEB (Ras Homolog Enriched in Brain (RHEB))
    蛋白类型
    Recombinant
    宿主
    • 8
    • 1
    • 1
    资源
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This RHEB protein is labelled with GST tag.
    原理
    Recombinant Human RHEB Protein (GST Tag)
    序列
    Met1-Met184
    产品特性
    Recombinant Human RHEB is produced by our E.coli expression system and the target gene encoding Met1-Met184 is expressed with a GST tag at the N-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product RHEB 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 10 mM GSH, pH 8.0.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    RHEB (Ras Homolog Enriched in Brain (RHEB))
    别名
    RHEB (RHEB 产品)
    别名
    RHEB2 Protein, RHEB Protein, rheb2 Protein, CG1081 Protein, DReb Protein, Dm Rheb Protein, DmRheb Protein, Dmel\CG1081 Protein, Q9VND8 Protein, RheB Protein, dRheb Protein, rheb Protein, Ras homolog, mTORC1 binding Protein, Ras homolog enriched in brain Protein, ras homolog enriched in brain Protein, Ras homolog, mTORC1 binding L homeolog Protein, RHEB Protein, Rheb Protein, rheb Protein, rheb.L Protein
    背景

    Background: GTP-Binding Protein Rheb (RHEB) is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. Highest levels of RHEB can be found in the skeletal and cardiac muscle, and it is vital in the regulation of growth and cell cycle progression due to its role in the Insulin/TOR/S6K signaling pathway. RHEB stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling, and it activates the protein kinase activity of mTORC1. RHEB has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, farnesylation of the protein is required for this activity.

    Synonym: GTP-Binding Protein Rheb, Ras Homolog Enriched in Brain, RHEB, RHEB2

    分子量
    20.4 kDa
    UniProt
    Q15382
    途径
    RTK signaling
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