MAPKAP Kinase 3 Protein (GST tag)
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- 抗原 See all MAPKAP Kinase 3 (MAPKAPK3) 蛋白
- MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This MAPKAP Kinase 3 protein is labelled with GST tag.
- 原理
- Recombinant Human MAPKAPK3 Protein (GST Tag)
- 序列
- Met 1-Gln 382
- 产品特性
- A DNA sequence encoding the full length of human MAPKAPK3 (NP_004626.1) (Met 1-Gln 382) was expressed with the GST tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product MAPKAPK3 蛋白
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Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3) (AA 1-382) protein (GST tag)
MAPKAPK3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA, KAA
Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3) (AA 272-382) protein (GST tag)MAPKAPK3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3) (AA 1-382) protein (Strep Tag)Crystallography grade MAPKAPK3 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3) (AA 1-384) protein (Strep Tag)Crystallography grade MAPKAPK3 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3) (Active) protein (Myc-DYKDDDDK Tag)MAPKAPK3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining Func, STD, AbP, PI Active
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile 50 mM Tris, 100 mM NaCl, pH 7.5, 0.25 mM DTT, 0.1 mM EDTA, 0.5 mM PMSF, 10 % glycerol
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
- 别名
- MAPKAPK3 (MAPKAPK3 产品)
- 别名
- 3PK Protein, MAPKAP-K3 Protein, MAPKAP3 Protein, MAPKAPK-3 Protein, MK-3 Protein, AI874665 Protein, MK3 Protein, MapkKapk3 Protein, MAPKAPK3 Protein, mapkapk3 Protein, MGC154360 Protein, 3pk Protein, mapkap3 Protein, zgc:158342 Protein, mitogen-activated protein kinase-activated protein kinase 3 Protein, mitogen-activated protein kinase-activated protein kinase 3 S homeolog Protein, MAPKAPK3 Protein, Mapkapk3 Protein, mapkapk3.S Protein, mapkapk3 Protein
- 背景
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Background: The MAPKAP kinases are a group of MAP kinase substrates which are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identifed and serve as substrates for the ERK and p38 MAP kinases. Mitogen-activated protein (MAP) kinase-activated protein kinase 3, also known as MAPKAPK-3 and 3pK, is a member of the Ser/Thr protein kinase family. It is Widely expressed in human tissues, with a higher expression level observed in heart and skeletal muscle. No expression in brain. MAPKAPK-3 is unique since it was shown to be activated by three members of the MAPK family, namely extracellular-signal-regulated kinase (ERK), p38, and Jun-N-terminal kinase (JNK). It is highly activated both by mitogens and by stress-inducing agents or proinflammatory cytokines, and translocates to the cytoplasm from nucleus. MAPKAPK-3 is exclusively activated via the classical MAPK cascade, while stress-induced activation of MAPKAPK-3 is mainly mediated by p38, however the mechanism defining the specificity remains unknown.
Synonym: 3PK,MAPKAP-K3,MAPKAP3,MAPKAPK-3,MK-3
- 分子量
- 69 kDa
- NCBI登录号
- NP_004626
- 途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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