LAMP1 Protein (Fc Tag)
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- 抗原 See all LAMP1 蛋白
- LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 人细胞
- 标记
- This LAMP1 protein is labelled with Fc Tag.
- 原理
- Recombinant Human LAMP1/CD107a Protein (Fc Tag)(Active)
- 序列
- Ala29-Met382
- 产品特性
- Recombinant Human Lysosome-Associated Membrane Glycoprotein 1 is produced by our Mammalian expression system and the target gene encoding Ala29-Met382 is expressed with a Fc tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human LGALS3(Cat: PKSH032474) at 2μg/ml(100 μl/well) can bind Human LAMP1-Fc. The ED50 of Human LAMP1-Fc is 1.994 ug/ml .
- Top Product
- Discover our top product LAMP1 蛋白
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Lysosomal-Associated Membrane Protein 1 (LAMP1) protein (His tag)
LAMP1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 294-381) protein (His-IF2DI Tag)LAMP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Lysosomal-Associated Membrane Protein 1 (LAMP1) protein (Fc Tag)LAMP1 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 92 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
- 别名
- LAMP1/CD107a (LAMP1 产品)
- 别名
- CD107a Protein, LAMPA Protein, LGP120 Protein, AI196048 Protein, Lamp-1 Protein, LEP100 Protein, LAMP-1 Protein, LGP-A Protein, Lgpa Protein, Lysosome-associated membrane protein 1 Protein, cd107a Protein, lamp-1 Protein, lamp1 Protein, lampa Protein, lgp120 Protein, rexp76 Protein, lysosomal associated membrane protein 1 Protein, lysosomal-associated membrane protein 1 Protein, lysosomal-associated membrane protein 1 L homeolog Protein, LAMP1 Protein, Lamp1 Protein, lamp1.L Protein
- 背景
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Background: Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belonging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell metastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells(PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
Synonym: Lysosome-Associated Membrane Glycoprotein 1, LAMP-1, Lysosome-Associated Membrane Protein 1, CD107 Antigen-Like Family Member A, CD107a, LAMP1,CD107a,LAMPA,LGP120
- 分子量
- 65.5 kDa
- UniProt
- P11279
- 途径
- Autophagy
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