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LYVE1 Protein (His tag)

LYVE1 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318754
发货至: 中国
  • 抗原 See all LYVE1 蛋白
    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
    蛋白类型
    Recombinant
    宿主
    • 6
    • 5
    资源
    • 6
    • 1
    • 1
    • 1
    • 1
    人细胞
    标记
    This LYVE1 protein is labelled with His tag.
    原理
    Recombinant Human LYVE1/HAR Protein (His Tag)
    序列
    Leu20-Thr 238
    产品特性
    Recombinant Human Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is produced by our Mammalian expression system and the target gene encoding Leu20-Thr238 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product LYVE1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-Citrate,1 50 mM NaCl, pH 7.0.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
    别名
    LYVE1/HAR (LYVE1 产品)
    别名
    LYVE1 Protein, XLKD1 Protein, CRSBP-1 Protein, HAR Protein, LYVE-1 Protein, 1200012G08Rik Protein, Crsbp-1 Protein, Lyve-1 Protein, Xlkd1 Protein, lymphatic vessel endothelial hyaluronic receptor 1a Protein, lymphatic vessel endothelial hyaluronan receptor 1 Protein, lyve1a Protein, LYVE1 Protein, Lyve1 Protein
    背景

    Background: Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

    Synonym: Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1, LYVE-1, Cell Surface Retention Sequence-Binding Protein 1, CRSBP-1, Extracellular Link Domain-Containing Protein 1, Hyaluronic Acid Receptor, LYVE1, CRSBP1, HAR, XLKD1

    分子量
    24.6 kDa
    UniProt
    Q9Y5Y7
    途径
    Glycosaminoglycan Metabolic Process
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