LYVE1 Protein (Soluble) (His tag)
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- 抗原 See all LYVE1 蛋白
- LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
- 蛋白类型
- Recombinant
- 产品特性
- Soluble
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宿主
- 小鼠
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资源
- Insect Cells
- 标记
- This LYVE1 protein is labelled with His tag.
- 序列
- ADLVQDLSIS TCRIMGVALV GRNKNPQMNF TEANEACKML GLTLASRDQV ESAQKSGFET CSYGWVGEQF SVIPRIFSNP RCGKNGKGVL IWNAPSSQKF KAYCHNSSDT WVNSCIPEIV TTFYPVLDTQ TPATEFSVSS SAYLASSPDS TTPVSATTRA PPLTSMARKT KKICITEVYT EPITMATETE AFVASGAAFK NEAAGHHHHH H
- 产品特性
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Length (AA): 211
Chromosomal location: 7, 7F2 - 纯度
- > 95 % by SDS-PAGE. Visualized by silver stain
- Top Product
- Discover our top product LYVE1 蛋白
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Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 1-322) protein (GST tag)
LYVE1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 20-238) protein (His tag)Crystallography grade LYVE1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 24-234) protein (His tag)Crystallography grade LYVE1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 20-322) protein (rho-1D4 tag)Crystallography grade LYVE1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 24-318) protein (rho-1D4 tag)Crystallography grade LYVE1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
- Not tested so far!
- 说明
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Soluble Receptors
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- The lyophilized sLYVE-1 is soluble in water and most aqueous buffers. The lyophilized sLYVE-1 should be reconstituted in PBS or medium to a concentration not lower than 50 μg/mL.
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C/-80 °C
- 储存方法
- Lyophilized samples are stable for greater than six months at -20 °C to -70 °C. Reconstituted sLYVE-1 should be stored in working aliquots at -20 °C.
- 有效期
- 6 months
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- 抗原
- LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
- 别名
- Lyve-1 (LYVE1 产品)
- 别名
- LYVE1 Protein, XLKD1 Protein, CRSBP-1 Protein, HAR Protein, LYVE-1 Protein, 1200012G08Rik Protein, Crsbp-1 Protein, Lyve-1 Protein, Xlkd1 Protein, lymphatic vessel endothelial hyaluronic receptor 1a Protein, lymphatic vessel endothelial hyaluronan receptor 1 Protein, lyve1a Protein, LYVE1 Protein, Lyve1 Protein
- 背景
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A DNA sequence encoding the extracellular domain of mouse LYVE-1 (Met1 – Gly228) was fused to a C-terminal His-tag (6xHis) and expressed in insect cells. Based on N-terminal sequence analysis, the primary structure of recombinant mature sLYVE-1 starts at Ala24. sLYVE-1 has a calculated monomeric molecular mass of about 25 kDa but as a result of glycosylation, migrates at approximately 35 - 45 kDa under reducing conditions in SDS-PAGE. LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Synonyms: Lyve1, Xlkd1, Lyve-1, Crsbp-1, 1200012G08Rik - 分子量
- 35.0 - 45.0 kDa
- NCBI登录号
- NP_444477, NM_053247
- UniProt
- Q8BHC0
- 途径
- Glycosaminoglycan Metabolic Process
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