Kallikrein 11 Protein (KLK11) (His tag)
-
- 抗原 See all Kallikrein 11 (KLK11) 蛋白
- Kallikrein 11 (KLK11)
- 蛋白类型
- Recombinant
- 生物活性
- Active
-
宿主
- 人
-
资源
- HEK-293 Cells
- 标记
- This Kallikrein 11 protein is labelled with His tag.
- 原理
- Recombinant Human Kallikrein 11/KLK11 Protein (His Tag)(Active)
- 序列
- Met 1-Asn 250
- 产品特性
- A DNA sequence encoding the human KLK11 isoform 1 (NP_006844.1) (Met 1-Asn 250) with a C-terminal polyhistidine tag was expressed.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to cleave a colorimetric peptide substrate D-Val-Leu-Lys-ThioBenzyl ester (VLK-SBzl), in the presence of 5,5'Dithio-bis (2-nitrobenzoic acid) (DTNB) (Edwards, K.M. et al.,1999, J. Biol. Chem. 274: 30468). The specific activity is >200 pmoles/min/μg.(Activation description: The proenzyme needs to be activated by Thermolysin for an activated form)
- Top Product
- Discover our top product KLK11 蛋白
-
Kallikrein 11 (KLK11) protein (His tag)
KLK11 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Kallikrein 11 (KLK11) (AA 1-250) protein (GST tag)KLK11 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Kallikrein 11 (KLK11) (AA 54-188) protein (His tag)Crystallography grade KLK11 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Kallikrein 11 (KLK11) (AA 189-282) protein (His tag)Crystallography grade KLK11 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Kallikrein 11 (KLK11) (AA 54-282) protein (His tag)Crystallography grade KLK11 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Kallikrein 11 (KLK11) (AA 48-276) protein (His tag)Crystallography grade KLK11 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- Kallikrein 11 (KLK11)
- 别名
- Kallikrein 11/KLK11 (KLK11 产品)
- 别名
- KLK11 Protein, 2310015I08Rik Protein, Prss20 Protein, TLSP Protein, PRSS20 Protein, kallikrein related peptidase 11 Protein, kallikrein related-peptidase 11 Protein, kallikrein-related peptidase 11 Protein, KLK11 Protein, Klk11 Protein
- 背景
-
Background: kallikrein-related peptidase 11 (KLK11), also known as hippostasin, trypsin-like serine protease and PRSS20, is a member of human tissue kallikrein family. It is a subgroup of serine proteases with diverse physiological functions, which is implicated in carcinogenesis and some with potential that serving as novel biomarkers for ovarian and prostate cancer and other diseases. The KLK11 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Two alternatively spliced forms exist, resulting in 250 (isoform 1) and 282 (isoform 2) amino acid sequences. Isoform 2 is identical to isoform 1, except for an inserted 32 amino acid segment. Isoform 1 is predominantly expressed in brain whereas isoform 2 is preferentially expressed in prostate.
Synonym: Kallikrein-11, hK11, Hippostasin, Serine Protease 20, Trypsin-Like Protease, KLK11, PRSS20, TLSP
- 分子量
- 27 kDa
- NCBI登录号
- NP_006844
- 途径
- Complement System
-
