Kallikrein 11 Protein (KLK11) (AA 19-250) (His tag)
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Quick Overview for Kallikrein 11 Protein (KLK11) (AA 19-250) (His tag) (ABIN7319354)
抗原
See all Kallikrein 11 (KLK11) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 19-250
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标记
- This Kallikrein 11 protein is labelled with His tag.
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原理
- Recombinant Human Kallikrein 11/KLK11 Protein (His Tag)
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序列
- Glu19-Asn250
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产品特性
- Recombinant Human Kallikrein 11 is produced by our Mammalian expression system and the target gene encoding Glu19-Asn250 is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 2 mM CaCl2, pH 8.0.
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- Kallikrein 11 (KLK11)
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别名
- Kallikrein 11/KLK11
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背景
- Hippostasin,KLK11,Kallikrein-11,PRSS20,Serine Protease 20,TLSP,Trypsin-Like Protease,hK11,Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide,a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.
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分子量
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Calculated MW: 26.3 kDa
Observed MW: 38 kDa
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NCBI登录号
- NP_006844
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途径
- Complement System
抗原
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