IFNAR1 Protein (His tag)
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- 抗原 See all IFNAR1 蛋白
- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- 人细胞
- 标记
- This IFNAR1 protein is labelled with His tag.
- 原理
- Recombinant Human IFNAR1/IFNAR Protein (His Tag)(Active)
- 序列
- Lys28-Lys436
- 产品特性
- Recombinant Human Interferon alpha/beta Receptor 1 is produced by our Mammalian expression system and the target gene encoding Lys28-Lys436 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human IFN alpha2b(Cat: PKSH033640) at 2μg/ml(100 μl/well) can bind Human IFNAR1-His.
- Top Product
- Discover our top product IFNAR1 蛋白
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Interferon alpha/beta Receptor 1 (IFNAR1) protein (His tag)
IFNAR1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >85 % as determined by reducing SDS-PAGE.
Interferon alpha/beta Receptor 1 (IFNAR1) protein (His tag)IFNAR1 宿主: 猕猴 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE.
Interferon alpha/beta Receptor 1 (IFNAR1) (AA 1-557) protein (GST tag)IFNAR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interferon alpha/beta Receptor 1 (IFNAR1) (AA 28-127) protein (GST tag)IFNAR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interferon alpha/beta Receptor 1 (IFNAR1) (Active) protein (His tag)IFNAR1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
- 别名
- IFNAR1/IFNAR (IFNAR1 产品)
- 别名
- ifnar1 Protein, IFNAR1 Protein, CD118 Protein, Ifar Protein, Ifnar Protein, Ifrc Protein, Infar Protein, AVP Protein, IFN-alpha-REC Protein, IFNAR Protein, IFNBR Protein, IFRC Protein, IFN-R-1 Protein, interferon alpha and beta receptor subunit 1 Protein, interferon-alpha/beta receptor alpha chain-like Protein, interferon (alpha and beta) receptor 1 Protein, interferon alpha/beta receptor 1 Protein, IFNAR1 Protein, ifnar1 Protein, Ifnar1 Protein, LOC609830 Protein
- 背景
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Background: The Interferon-α/β Receptor 1 (IFN-α/β R1) is a receptor which binds Type I Interferons including Interferon-α and -β. It is a cell surface receptor and heteromeric receptor composed of one chain with two subunits referred to as IFNAR1 and IFNAR2. IFN-α/β R1, in association with IFN-α/β R2, is required for propagating antiviral signal transduction triggered by IFN-α and IFN-β. IFN-α/β R1 interacts very weakly or not at all with type 1 interferons and does not stably interact with IFN-α/β R2. Ligands associate with IFN-α/β R2, and this complex subsequently forms a stable ternary assembly with IFN-α/β R1. IFN-α/β R1 also associates with IFN-γ R2 even in the absence of IFN-γ stimulation. Human IFN-α/β R1 contains a nuclear localization signal in its extracellular domain that is required for receptor translocation to the nucleus following interaction with ligand. Interferon stimulation results in an immunologic response that is especially associated with viruses.
Synonym: Interferon Alpha/Beta Receptor 1, IFN-R-1, IFN-Alpha/Beta Receptor 1, Cytokine Receptor Class-II Member 1, Cytokine Receptor Family 2 Member 1, CRF2-1, Type I Interferon Receptor 1,IFNAR1,IFNAR,AVP,IFN-alpha-REC
- 分子量
- 48.2 kDa
- UniProt
- P17181
- 途径
- JAK/STAT Signaling, Hepatitis C
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