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IFNAR1 Protein (His tag)

IFNAR1 宿主: 猕猴 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7320999
发货至: 中国
  • 抗原 See all IFNAR1 蛋白
    IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
    蛋白类型
    Recombinant
    宿主
    • 14
    • 7
    • 2
    • 1
    • 1
    猕猴
    资源
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    人细胞
    标记
    This IFNAR1 protein is labelled with His tag.
    原理
    Recombinant Rhesus macaque IFNAR1 Protein (His Tag)
    序列
    Ala25-Lys437
    产品特性
    Recombinant Rhesus macaque IFNAR1 is produced by our Mammalian expression system and the target gene encoding Ala25-Lys437 is expressed with a 6His tag at the C-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product IFNAR1 蛋白
  • 说明

    70-120 kDa

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
    别名
    IFNAR1 (IFNAR1 产品)
    别名
    ifnar1 Protein, IFNAR1 Protein, CD118 Protein, Ifar Protein, Ifnar Protein, Ifrc Protein, Infar Protein, AVP Protein, IFN-alpha-REC Protein, IFNAR Protein, IFNBR Protein, IFRC Protein, IFN-R-1 Protein, interferon alpha and beta receptor subunit 1 Protein, interferon-alpha/beta receptor alpha chain-like Protein, interferon (alpha and beta) receptor 1 Protein, interferon alpha/beta receptor 1 Protein, IFNAR1 Protein, ifnar1 Protein, Ifnar1 Protein, LOC609830 Protein
    背景

    Background: Interferon?alpha/beta receptor 1 (IFN? alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

    Synonym: Alpha-type antiviral protein, AVP, beta-type antiviral protein, CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, IFN-alpha/beta R1, IFN-alpha/beta receptor 1, IFN-alpha-REC, IFNAR, IFNAR1, IFN-aR1, IFNBR, IFNbR1, IFN-bR1, IFN-R-1

    分子量
    48.4 kDa
    UniProt
    H9FTY3
    途径
    JAK/STAT Signaling, Hepatitis C
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