GM2A Protein (His tag)
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- 抗原 See all GM2A 蛋白
- GM2A (GM2 Ganglioside Activator (GM2A))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This GM2A protein is labelled with His tag.
- 原理
- Recombinant Human GM2A Protein (Human Cells, His Tag)
- 序列
- Ser32-Ile193
- 产品特性
- Recombinant Human Ganglioside GM2 activator is produced by our Mammalian expression system and the target gene encoding Ser32-Ile193 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product GM2A 蛋白
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GM2 Ganglioside Activator (GM2A) (AA 26-193) protein (His tag)
GM2A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
GM2 Ganglioside Activator (GM2A) (AA 1-193) protein (GST tag)GM2A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
GM2 Ganglioside Activator (GM2A) (AA 94-193) protein (GST tag)GM2A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl, pH 7.5.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- GM2A (GM2 Ganglioside Activator (GM2A))
- 别名
- GM2A (GM2A 产品)
- 别名
- GM2A Protein, fb96e04 Protein, fb96e10 Protein, wu:fb96e04 Protein, wu:fb96e10 Protein, zgc:110188 Protein, MGC84154 Protein, GM2-AP Protein, SAP-3 Protein, AA408702 Protein, AW215435 Protein, GM2 ganglioside activator Protein, GM2 ganglioside activator L homeolog Protein, GM2 ganglioside activator protein Protein, Gm2a Protein, GM2A Protein, gm2a Protein, gm2a.L Protein
- 背景
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Background: Ganglioside GM2 activator (GM2A) is a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A (HEXB). HEXB together with GM2A, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. GM2A accommodate several single chain phospholipids and fatty acids, is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T-cell activation through lipid presentation. It extracts single GM2 Molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
Synonym: Ganglioside GM2 activator,Cerebroside sulfate activator protein,GM2-AP,Sphingolipid activator protein 3,SAP-3
- 分子量
- 18.6 kDa
- UniProt
- P17900
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