FCGR3A Protein (His tag)
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- 抗原 See all FCGR3A 蛋白
- FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
- 蛋白类型
- Recombinant
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宿主
- Cynomolgus
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资源
- 人细胞
- 标记
- This FCGR3A protein is labelled with His tag.
- 原理
- Recombinant Cynomolgus Fc gamma RIIIA/FCGR3A/CD16a (C-6His)
- 序列
- Glu21-Gly206
- 产品特性
- Recombinant Cynomolgus Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A is produced by our Mammalian expression system and the target gene encoding Glu21-Gly206 is expressed with a 6His tag at the C-terminus.
- 纯度
- >95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product FCGR3A 蛋白
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Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 17-208) protein (His-Avi Tag)
FCGR3A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) protein (His-Avi Tag,Biotin)FCGR3A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 17-254) protein (GST tag)FCGR3A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 17-208) (Active) protein (His tag)FCGR3A 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) protein (His tag)FCGR3A 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (Active) protein (His tag,AVI tag)FCGR3A 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (Active) protein (His tag)FCGR3A 宿主: 人 宿主: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE. Active
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (Active) protein (His tag)FCGR3A 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (Active) protein (Biotin,His-Avi Tag)FCGR3A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. Active
Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A) (AA 32-215) (Active) protein (His tag)FCGR3A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
- 别名
- Fc gamma RIIIA/FCGR3A/CD16a (FCGR3A 产品)
- 别名
- CD16 Protein, CD16A Protein, FCG3 Protein, FCGR3 Protein, FCGRIII Protein, FCR-10 Protein, FCRIII Protein, FCRIIIA Protein, IGFR3 Protein, Fcgr4 Protein, Fc fragment of IgG receptor IIIa Protein, FCGR3A Protein, Fcgr3a Protein
- 背景
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Background: Receptors for the Fc region of immunoglobin G (FcγR) are divided into three classes and FcγRIII is a multifunctional, low/intermediate affinity receptor. In humans, FcγRIII is expressed as two distinct forms (FcγRIIIA and FcγRIIIB) that are encoded by two different but highly homologous genes in a cell type-specific manner. FcγRIIIB is a low-affinity, GPI-linked receptor expressed by neutrophils and eosinophils, whereas FcγRIIIA is an intermediate affinity polypeptide-anchored transmembrane glycoprotein expressed by a subset of T lymphocytes, natural killer (NK) cells, monocytes, and macrophages. The FcγRIIIA receptor is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), mast cell degranulation, and clearance of immune complexes. FcγRIIIA has an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain and delivers an activation signal in the immune responses. Aberrant expression or mutations in this gene is implicated in susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia. In humans, it is a 50 -70 kD type I transmembrane activating receptor. The FcγRIIIA cDNA encodes 254 amino acid including a 16aa signal sequence, 191 amino acid ECD with two C2-type Ig-like domains, five potential N-glycosylation sites, a 22 amino acid transmembrane sequence and a 25 amino acid cytoplasmic domain.
Synonym: Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A, CD16a Antigen, Fc-Gamma RIII-Alpha, Fc-Gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc Receptor III-2, CD16a, FCGR3A, CD16A, FCG3, FCGR3, IGFR3
- 分子量
- 22 kDa
- UniProt
- A0A140HDP8
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