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FCGR3A Protein (His tag)

FCGR3A 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
产品编号 ABIN6961127
发货至: 中国
  • 抗原 See all FCGR3A 蛋白
    FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
    蛋白类型
    Recombinant
    宿主
    • 21
    • 3
    • 3
    • 1
    资源
    • 15
    • 6
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This FCGR3A protein is labelled with His tag.
    原理
    Recombinant human FCGR3A protein(F176V) with C-terminal 6xHis tag
    特异性
    FCGR3A (Gly17-Gly206) (F176V) 6xHis tag
    产品特性
    Extracellular Domain Protein
    纯化方法
    affinity purification
    纯度
    The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product FCGR3A 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute with deionized water
    缓冲液
    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存液
    Without preservative
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    FCGR3A (Fc Fragment of IgG, Low Affinity IIIa, Receptor (CD16a) (FCGR3A))
    别名
    FCGR3A (FCGR3A 产品)
    别名
    CD16 Protein, CD16A Protein, FCG3 Protein, FCGR3 Protein, FCGRIII Protein, FCR-10 Protein, FCRIII Protein, FCRIIIA Protein, IGFR3 Protein, Fcgr4 Protein, Fc fragment of IgG receptor IIIa Protein, FCGR3A Protein, Fcgr3a Protein
    背景
    Synonymes: FCGR3A,CD16A,FCG3,FCGR3,IGFR3
    Description: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量
    predicted molecular mass of 22.3 kDa after removal of the signal peptide.
    基因ID
    2214
    UniProt
    P08637
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