eIF4EBP1 Protein (His tag)
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- 抗原 See all eIF4EBP1 (EIF4EBP1) 蛋白
- eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This eIF4EBP1 protein is labelled with His tag.
- 原理
- Recombinant Human 4E-BP1/EIF4EBP1 Protein (His Tag)
- 序列
- Met 1-Ile118
- 产品特性
- Recombinant Human Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Ile118 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product EIF4EBP1 蛋白
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Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 1-118) protein (His tag)
EIF4EBP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 1-118) protein (GST tag)EIF4EBP1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 2-118) protein (His tag)Crystallography grade EIF4EBP1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 2-117) protein (His tag)Crystallography grade EIF4EBP1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
- 别名
- 4E-BP1/EIF4EBP1 (EIF4EBP1 产品)
- 别名
- 4E-BP1 Protein, 4EBP1 Protein, BP-1 Protein, PHAS-I Protein, 4e-bp1 Protein, AA959816 Protein, 153432_at Protein, 43-BP Protein, 4E-BP Protein, 4EBP Protein, 4e-bp Protein, 4eBP Protein, 4ebp Protein, BcDNA.HL08053 Protein, BcDNA:HL08053 Protein, CG8846 Protein, CT8705 Protein, Dm 4E-BP Protein, Dmel\\CG8846 Protein, Phas1 Protein, Thor/EIF4EBP Protein, anon-WO0172774.158 Protein, d4E-BP Protein, d4E-BP1 Protein, d4EBP Protein, d4e-bp Protein, d4eBP Protein, dthor Protein, eIF4E-BP Protein, l(2)06270 Protein, l(2)k07736 Protein, l(2)k13517 Protein, pp20 Protein, thor Protein, EIF4EBP1 Protein, fc04h09 Protein, wu:fc04h09 Protein, zgc:64137 Protein, eukaryotic translation initiation factor 4E binding protein 1 Protein, CG8846 gene product from transcript CG8846-RA Protein, EIF4EBP1 Protein, Eif4ebp1 Protein, Thor Protein, eif4ebp1 Protein
- 背景
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Background: Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) is a number of the eIF4E-binding protein family. 4EBP1 regulates eIF4E activity by preventing its assembly into the eIF4F complex. 4EBP1 mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. Non-phosphorylated 4EBP1 competes with EIF4G1/EIF4G3 to interact with EIF4E. 4EBP1 is phosphorylated in response to various signals including insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. 4EBP1 has a role in progression of breast neoplasms through cell signaling.
Synonym: Eukaryotic Translation Initiation Factor 4E-Binding Protein 1, 4E-BP1, eIF4E-Binding Protein 1, Phosphorylated Heat- and Acid-Stable Protein Regulated by Insulin 1, PHAS-I, EIF4EBP1,4E-BP1,4EBP1,BP-1
- 分子量
- 14.7 kDa
- UniProt
- Q13541
- 途径
- MAPK Pathway, PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Regulation of Cell Size, BCR Signaling
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