EPH Receptor A7 Protein (EPHA7) (His tag)
-
- 抗原 See all EPH Receptor A7 (EPHA7) 蛋白
- EPH Receptor A7 (EPHA7)
- 蛋白类型
- Recombinant
- 生物活性
- Active
-
宿主
- 大鼠
-
资源
- HEK-293 Cells
- 标记
- This EPH Receptor A7 protein is labelled with His tag.
- 原理
- Recombinant Rat EphA7/EHK3 Protein (His Tag)(Active)
- 序列
- Met1-Ser539
- 产品特性
- A DNA sequence encoding the rat EPHA7 (P54759)(Met1-Ser539) was expressed with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
- Biological Activity Comment
- Immobilized rat EPHA7-His at 10 μg/ml (100 μl/well) can bind mouse EFNA4-Fc, The EC50 of mouse EFNA4-Fc is 10.0-23.4 ng/ml.
- Top Product
- Discover our top product EPHA7 蛋白
-
EPH Receptor A7 (EPHA7) (AA 1-279) protein (GST tag)
EPHA7 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
EPH Receptor A7 (EPHA7) (AA 231-330) protein (GST tag)EPHA7 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
EPH Receptor A7 (EPHA7) (Active) protein (GST tag,His tag)EPHA7 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 94 % as determined by reducing SDS-PAGE. Active
EPH Receptor A7 (EPHA7) (Active) protein (Fc Tag)EPHA7 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
EPH Receptor A7 (EPHA7) (Active) protein (His tag)EPHA7 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- EPH Receptor A7 (EPHA7)
- 别名
- EphA7/EHK3 (EPHA7 产品)
- 别名
- fc51g03 Protein, wu:fc51g03 Protein, si:dkey-23k6.1 Protein, EHK3 Protein, HEK11 Protein, Cek11 Protein, Ebk Protein, Ehk3 Protein, Hek11 Protein, Mdk1 Protein, CEPHA7 Protein, EPH receptor A7 Protein, eph receptor A7 Protein, ephrin type-B receptor 1-B Protein, Eph receptor A7 Protein, EPHA7 Protein, epha7 Protein, LOC100166161 Protein, Epha7 Protein
- 背景
-
Background: Ephrin type-A receptor 7, also known as EphA7, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. The Eph family of receptor tyrosine kinases (comprising EphA and EphB receptors) has been implicated in synapse formation and the regulation of synaptic function and plasticity6. Eph receptor-mediated signaling, which is triggered by ephrins7, probably modifies the properties of synapses during synaptic activation and remodeling. Ephrin receptors are components of cell signalling pathways involved in animal growth and development, forming the largest sub-family of receptor tyrosine kinases (RTKs). Ligand-mediated activation of Ephs induce various important downstream effects and Eph receptors have been studied for their potential roles in the development of cancer. Down-regulation of EphA7 secondary to hypermethylation has been reported in colorectal cancer. The expression of EphA7 was reduced in all tested gastric cancer cell lines, however, there is marked variability in expression among gastric carcinoma specimens. EphA7 may have roles in the pathogenesis and development of gastric carcinomas.
Synonym: EPHA7,Ehk-3,Ehk3
- 分子量
- 58.9 kDa
- UniProt
- P54759
- 途径
- RTK signaling
-
