EPH Receptor A7 Protein (EPHA7) (GST tag,His tag)
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- 抗原 See all EPH Receptor A7 (EPHA7) 蛋白
- EPH Receptor A7 (EPHA7)
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This EPH Receptor A7 protein is labelled with GST tag,His tag.
- 原理
- Recombinant Human EphA7/EHK3 Protein (His & GST Tag)(Active)
- 序列
- Gly579-Val998
- 产品特性
- A DNA sequence encoding the human EPHA7 (NP_004431) (Gly579-Val998) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- 纯度
- > 94 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- The specific activity was determined to be 9.5 nmol/min/mg using Poly(Glu:Tyr) 4:1 as substrate.
- Top Product
- Discover our top product EPHA7 蛋白
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EPH Receptor A7 (EPHA7) (AA 1-279) protein (GST tag)
EPHA7 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
EPH Receptor A7 (EPHA7) (AA 231-330) protein (GST tag)EPHA7 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
EPH Receptor A7 (EPHA7) (Active) protein (Fc Tag)EPHA7 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
EPH Receptor A7 (EPHA7) (Active) protein (His tag)EPHA7 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
EPH Receptor A7 (EPHA7) (Active) protein (His tag)EPHA7 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- EPH Receptor A7 (EPHA7)
- 别名
- EphA7/EHK3 (EPHA7 产品)
- 别名
- fc51g03 Protein, wu:fc51g03 Protein, si:dkey-23k6.1 Protein, EHK3 Protein, HEK11 Protein, Cek11 Protein, Ebk Protein, Ehk3 Protein, Hek11 Protein, Mdk1 Protein, CEPHA7 Protein, EPH receptor A7 Protein, eph receptor A7 Protein, ephrin type-B receptor 1-B Protein, Eph receptor A7 Protein, EPHA7 Protein, epha7 Protein, LOC100166161 Protein, Epha7 Protein
- 背景
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Background: Ephrin type-A receptor 7, also known as EphA7, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. The Eph family of receptor tyrosine kinases (comprising EphA and EphB receptors) has been implicated in synapse formation and the regulation of synaptic function and plasticity6. Eph receptor-mediated signaling, which is triggered by ephrins7, probably modifies the properties of synapses during synaptic activation and remodeling. Ephrin receptors are components of cell signalling pathways involved in animal growth and development, forming the largest sub-family of receptor tyrosine kinases (RTKs). Ligand-mediated activation of Ephs induce various important downstream effects and Eph receptors have been studied for their potential roles in the development of cancer. Down-regulation of EphA7 secondary to hypermethylation has been reported in colorectal cancer. The expression of EphA7 was reduced in all tested gastric cancer cell lines, however, there is marked variability in expression among gastric carcinoma specimens. EphA7 may have roles in the pathogenesis and development of gastric carcinomas.
Synonym: Ephrin Type-A Receptor 7, EPH Homology Kinase 3, EHK-3, EPH-Like Kinase 11, EK11, hEK11, EPHA7, EHK3, HEK11
- 分子量
- 75.2 kDa
- NCBI登录号
- NP_004431
- 途径
- RTK signaling
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