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Complement Factor H Protein (CFH) (His tag)

CFH 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318329
发货至: 中国
  • 抗原 See all Complement Factor H (CFH) 蛋白
    Complement Factor H (CFH)
    蛋白类型
    Recombinant
    宿主
    • 6
    • 4
    • 2
    • 1
    资源
    • 6
    • 2
    • 2
    • 2
    • 1
    人细胞
    标记
    This Complement Factor H protein is labelled with His tag.
    原理
    Recombinant Human Complement Factor H/CFH Protein (His Tag)
    序列
    Glu19-Leu449
    产品特性
    Recombinant Human Complement factor H is produced by our Mammalian expression system and the target gene encoding Glu19-Leu449 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CFH 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of PBS,20 % Glycerol,5 % Trehalose, pH 7.4.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    Complement Factor H (CFH)
    别名
    Complement Factor H/CFH (CFH 产品)
    别名
    AHUS1 Protein, AMBP1 Protein, ARMD4 Protein, ARMS1 Protein, CFHL3 Protein, FH Protein, FHL1 Protein, HF Protein, HF1 Protein, HF2 Protein, HUS Protein, Mud-1 Protein, NOM Protein, Sas-1 Protein, Sas1 Protein, Fh Protein, CFH Protein, im:7147412 Protein, si:ch211-207o17.2 Protein, fH Protein, armd4 Protein, arms1 Protein, cfh Protein, cfhl3 Protein, fhl1 Protein, hf1 Protein, hf2 Protein, hus Protein, complement factor H Protein, complement component factor h Protein, complement factor H-related protein 5 Protein, complement factor H L homeolog Protein, CFH Protein, Cfh Protein, cfh Protein, LOC100399888 Protein, LOC100733902 Protein, cfh.L Protein
    背景

    Background: Complement Factor H (CFH) is a secreted protein which is a member of the regulators of complement activation family and is a complement control protein. It is expressed by the liver and secreted in plasma. Its principal function is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue. Factor H regulates complement activation on self cells and surfaces by possessing both cofactor activity for the Factor I mediated C3b cleavage, and decay accelerating activity against the alternative pathway C3-convertase, C3bBb. Factor H exerts its protective action on self cells and self surfaces but not on the surfaces of bacteria or viruses, because it binds to glycosaminoglycans (GAGs) that are generally present on host cells but not, normally, on pathogen surfaces.

    Synonym: AHUS1,AMBP1,ARMD4,ARMS1,CFHL3,FH,FHL1,HF,HF1,HF2,HUS

    分子量
    50.0 kDa
    途径
    Complement System, Cellular Response to Molecule of Bacterial Origin
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