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Elastase 4 Protein (His tag)

CTRC 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319317
发货至: 中国
  • 抗原 See all Elastase 4 (CTRC) products
    Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 3
    • 3
    • 1
    资源
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    人细胞
    标记
    This Elastase 4 protein is labelled with His tag.
    原理
    Recombinant Human Chymotrypsin C Protein (His Tag)
    序列
    Cys17-Leu268
    产品特性
    Recombinant Human Chymotrypsin-C is produced by our Mammalian expression system and the target gene encoding Cys17-Leu268 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))
    别名
    Chymotrypsin C (CTRC 产品)
    别名
    CLCR Protein, ELA4 Protein, 1810044E12Rik Protein, bPTLP Protein, chymotrypsin C Protein, chymotrypsin-C Protein, chymotrypsin C (caldecrin) Protein, CTRC Protein, LOC478220 Protein, Ctrc Protein
    背景

    Background: Chymotrypsin C (CTRC) is a member of the peptidase S1 family. CTRC is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. CTRC has broad substrate specificity, but prefers tocleave on the carboxyl side of hydrophobic residues. CTRC is expressed primarily in the pancreas, and is secreted into the digestive tract. CTRC plays a protective role in the pancreas by mitigating premature trypsinogen activation through degradation. It has been proposed that CTRC is a key regulator of digestive zymogen activation and is a physiological coactivator of digestive carboxypeptidases proCPA1 and proCPA2. The mutation of CTRC gene encodes the digestive enzyme CTRC contribute to the development of pancreatitis.

    Synonym: Chymotrypsin-C, Caldecrin, CTRC, CLCR

    分子量
    29.0 kDa
    UniProt
    Q99895
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