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Elastase 4 Protein (AA 17-268) (His tag)

CTRC 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN1096392
发货至: 中国
  • 抗原 See all Elastase 4 (CTRC) products
    Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))
    蛋白类型
    Recombinant
    产品特性
    AA 17-268
    宿主
    • 7
    • 3
    • 3
    • 1
    资源
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    人细胞
    标记
    This Elastase 4 protein is labelled with His tag.
    原理
    Recombinant Human Chymotrypsin-C/CTRC (C-6His)
    序列
    CGVPSFPPNL SARVVGGEDA RPHSWPWQIS LQYLKNDTWR HTCGGTLIAS NFVLTAAHCI SNTRTYRVAV GKNNLEVEDE EGSLFVGVDT IHVHKRWNAL LLRNDIALIK LAEHVELSDT IQVACLPEKD SLLPKDYPCY VTGWGRLWTN GPIADKLQQG LQPVVDHATC SRIDWWGFRV KKTMVCAGGD GVISACNGDS GGPLNCQLEN GSWEVFGIVS FGSRRGCNTR KKPVVYTRVS AYIDWINEKM QLVDHHHHHH
    产品特性
    Recombinant Human Chymotrypsin-C/CTRC produced by transfected human cells is a secreted protein with sequence (Cys17-Leu268) of Human CTRC fused with a polyhistidine tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    过滤
    0.2 μm filtered
    内毒素水平
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • 限制
    仅限研究用
  • 状态
    Liquid
    溶解方式
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    注意事项
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    储存条件
    -80 °C
    储存方法
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    Elastase 4 (CTRC) (Chymotrypsin C (Caldecrin) (CTRC))
    别名
    chymotrypsin-c (CTRC 产品)
    别名
    CLCR Protein, ELA4 Protein, 1810044E12Rik Protein, bPTLP Protein, chymotrypsin C Protein, chymotrypsin-C Protein, chymotrypsin C (caldecrin) Protein, CTRC Protein, LOC478220 Protein, Ctrc Protein
    Sub Type
    Fusionprotein
    背景
    Chymotrypsin C (CTRC) is a member of the peptidase S1 family. CTRC is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. CTRC has broad substrate specificity, but prefers to cleave on the carboxyl side of hydrophobic residues. CTRC is expressed primarily in the pancreas, and is secreted into the digestive tract. CTRC plays a protective role in the pancreas by mitigating premature trypsinogen activation through degradation. It has been proposed that CTRC is a key regulator of digestive zymogen activation and is a physiological coactivator of digestive carboxypeptidases proCPA1 and proCPA2. The mutation of CTRC gene encodes the digestive enzyme CTRC contribute to the development of pancreatitis.
    Alternative Names: Chymotrypsin-C, Caldecrin, CTRC, CLCR
    分子量
    29 kDa
    UniProt
    Q99895
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