CCL11 蛋白
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- 抗原 See all CCL11 products
- CCL11 (Chemokine (C-C Motif) Ligand 11 (CCL11))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 原理
- Recombinant Human CCL11/Eotaxin Protein
- 序列
- Gly24-Pro97
- 产品特性
- Recombinant Human C-C Motif Chemokine 11 is produced by our E.coli expression system and the target gene encoding Gly24-Pro97 is expressed.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CCL11 (Chemokine (C-C Motif) Ligand 11 (CCL11))
- 别名
- CCL11/Eotaxin (CCL11 产品)
- 别名
- SCYA11 Protein, Scya11 Protein, eotaxin Protein, Eotaxin Protein, C-C motif chemokine ligand 11 Protein, chemokine (C-C motif) ligand 11 Protein, CCL11 Protein, Ccl11 Protein
- 背景
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Background: C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.
Synonym: Eotaxin, C-C Motif Chemokine 11, Eosinophil Chemotactic Protein, Small-Inducible Cytokine A11, CCL11, SCYA11
- 分子量
- 8.6 kDa
- UniProt
- P51671
- 途径
- Regulation of Actin Filament Polymerization, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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