CD27 Protein (His tag,Fc Tag)
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- 抗原 See all CD27 蛋白
- CD27 (CD27 Molecule (CD27))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This CD27 protein is labelled with His tag,Fc Tag.
- 原理
- Recombinant Mouse CD27/TNFRSF7 Protein (His & Fc Tag)(Active)
- 序列
- Met 1-Arg 182
- 产品特性
- A DNA sequence encoding the extracellular domain (Met 1-Arg 182) of mouse CD27 (NP_001028298.1) precursor was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
- 纯度
- > 94 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse CD27 at 2 μg/ml (100 μl/well) can bind biotinylated human CD70 with a linear range of 0.39-12.5 ng/ml.
- Top Product
- Discover our top product CD27 蛋白
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CD27 Molecule (CD27) (AA 21-192) protein (His tag)
CD27 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD27 Molecule (CD27) protein (Fc Tag)CD27 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
CD27 Molecule (CD27) (AA 21-192) protein (His tag)CD27 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD27 Molecule (CD27) (AA 24-182) protein (mFc Tag)CD27 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD27 Molecule (CD27) (AA 20-191) protein (Fc Tag)CD27 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD27 Molecule (CD27) (AA 1-260) protein (GST tag)CD27 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD27 Molecule (CD27) protein (mFc-His Tag)CD27 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD27 Molecule (CD27) (AA 21-192) (Active) protein (Fc Tag)CD27 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD27 Molecule (CD27) (AA 21-182) (Active) protein (Fc Tag)CD27 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD27 Molecule (CD27) protein (His tag,Fc Tag)CD27 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- CD27 (CD27 Molecule (CD27))
- 别名
- CD27/TNFRSF7 (CD27 产品)
- 别名
- TNFRSF7 Protein, S152 Protein, Tnfrsf7 Protein, Tp55 Protein, S152. LPFS2 Protein, T14 Protein, CD27 molecule Protein, CD27 antigen Protein, CD27 Protein, Cd27 Protein
- 背景
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Background: CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has important role in generation of T cell immunity, and is an apparently robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis.Immune CheckpointImmune Checkpoint Detection: Antibodies Immune Checkpoint Detection: ELISA Antibodies Immune Checkpoint Detection: IHC Antibodies Immune Checkpoint Detection: ICC Antibodies Immune Checkpoint Detection: FCM AntibodiesImmune Checkpoint ProteinsImmune Checkpoint Targets Co-stimulatory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: CD27 antigen; CD27L receptor; T-cell activation antigen CD27; Tumor necrosis factor receptor superfamily member 7;S152;Tnfrsf7;Tp55
- 分子量
- 46.2 kDa
- NCBI登录号
- NP_001028298
- 途径
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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