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CD27 Protein (His tag,Fc Tag)

CD27 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320754
发货至: 中国
  • 抗原 See all CD27 蛋白
    CD27 (CD27 Molecule (CD27))
    蛋白类型
    Recombinant
    宿主
    • 24
    • 10
    • 3
    • 3
    • 1
    小鼠
    资源
    • 19
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    人细胞
    标记
    This CD27 protein is labelled with His tag,Fc Tag.
    原理
    Recombinant Mouse CD27/TNFRSF7 Protein (Fc & His Tag)
    序列
    Pro24-Arg182
    产品特性
    Recombinant Mouse CD27 antigen is produced by our Mammalian expression system and the target gene encoding Pro24-Arg182 is expressed with a Fc, 6His tag at the C-terminus.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CD27 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    CD27 (CD27 Molecule (CD27))
    别名
    CD27/TNFRSF7 (CD27 产品)
    别名
    TNFRSF7 Protein, S152 Protein, Tnfrsf7 Protein, Tp55 Protein, S152. LPFS2 Protein, T14 Protein, CD27 molecule Protein, CD27 antigen Protein, CD27 Protein, Cd27 Protein
    背景

    Background: Mouse CD27 is a single-pass type I membrane protein which is a member of the tumor necrosis factor receptor superfamily. CD27 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-κB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

    Synonym: CD27 antigen, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7,S152,Tnfrsf7,Tp55

    分子量
    45.8 kDa
    NCBI登录号
    NP_001028298
    途径
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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