Caspase 10 Protein (His tag)
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- 抗原 See all Caspase 10 (CASP10) 蛋白
- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Caspase 10 protein is labelled with His tag.
- 原理
- Recombinant Human Caspase-10/CASP10 Protein (His Tag)
- 序列
- Val220-Ile480
- 产品特性
- Recombinant Human Caspase-10 is produced by our E.coli expression system and the target gene encoding Val220-Ile480 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product CASP10 蛋白
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Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 1-110) protein (GST tag)
CASP10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 19-187) protein (GST tag)CASP10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (AA 1-479) protein (GST tag)CASP10 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 25 mM HEPES, 10 mM DTT, pH 7.5.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
- 别名
- Caspase-10/CASP10 (CASP10 产品)
- 别名
- xCaspase-10 Protein, alps2 Protein, caspace-10 Protein, caspase-10 Protein, flice2 Protein, mch4 Protein, xCaspace-10 Protein, ALPS2 Protein, FLICE2 Protein, MCH4 Protein, caspase 10 S homeolog Protein, caspase 10 Protein, caspase-10 Protein, casp10.S Protein, casp10 Protein, CASP10 Protein, Casp10 Protein, LOC100848685 Protein
- 背景
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Background: Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granzyme B and autocatalytic activity generate the two active subunits: Caspase-10 subunit p23/17, Caspase-10 subunit p12. Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the execution-phase of cell apoptosis, the initiation and execution. Human caspases can be subdivided into three functional groups: cytokine activation (caspase-1, -4, -5, and -13), apoptosis initiation (caspase-2, -8, -9, -and -10), and apoptosis execution (caspase-3, -6, and -7). CASP10 cleaves and activates caspases 3 and 7, but itself is processed by caspase 8. Defects in CASP10 are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.
Synonym: Caspase-10, CASP-10, Apoptotic Protease Mch-4, FAS-Associated Death Domain Protein Interleukin-1B-Converting Enzyme 2, FLICE2, ICE-Like Apoptotic Protease 4, CASP10, MCH4
- 分子量
- 30.1 kDa
- 途径
- Apoptosis, Caspase Cascade in Apoptosis
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