Caspase 10 产品
(Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
Categories
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011].
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Featured Caspase 10 Categories
Caspase 10 抗体
High quality antibodies with extensive validation data.
Caspase 10 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Caspase 10 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Caspase 10 抗体
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
Human
Application
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- (9)
Cat. No.
ABIN7443104
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
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- (5)
Cat. No.
ABIN6260480
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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- (4)
Cat. No.
ABIN514026
Quantity
100 μg
Datasheet
Datasheet
Recommended Caspase 10 ELISA试剂盒
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Reactivity
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Reactivity
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- (1)
Cat. No.
ABIN6965451
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Datasheet
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Reactivity
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Analytical Method
Quantitative Sandwich ELISA
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- (1)
Cat. No.
ABIN1113980
Quantity
96 tests
Datasheet
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Reactivity
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Quantitative Competition ELISA
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Cat. No.
ABIN512873
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Recommended Caspase 10 蛋白
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Cat. No.
ABIN1348091
Quantity
10 μg
Datasheet
Datasheet
Reactivity
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Source
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Cat. No.
ABIN1348093
Quantity
10 μg
Datasheet
Datasheet
Reactivity
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Source
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Cat. No.
ABIN1348090
Quantity
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Datasheet
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Latest Publications for our Caspase 10 Products
: "Protective role of sodium selenite on histopathological lesions, decreased T-cell subsets and increased apoptosis of thymus in broilers intoxicated with aflatoxin B?." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 59, pp. 446-54, (2013) (PubMed).: "Carnitine sensitizes TRAIL-resistant cancer cells to TRAIL-induced apoptotic cell death through the up-regulation of Bax." in: Biochemical and biophysical research communications, Vol. 428, Issue 1, pp. 185-90, (2012) (PubMed).
: "Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation." in: Experimental neurology, Vol. 189, Issue 2, pp. 261-79, (2004) (PubMed).
: "Inactivating mutations of the caspase-10 gene in gastric cancer." in: Oncogene, Vol. 21, Issue 18, pp. 2919-25, (2002) (PubMed).
: "Molecular cloning and characterization of two novel pro-apoptotic isoforms of caspase-10." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10301-8, (1999) (PubMed).
: "Neurturin, a novel neurotrophic factor, is localized to mouse chromosome 17 and human chromosome 19p13.3." in: Genomics, Vol. 44, Issue 1, pp. 137-40, (1997) (PubMed).
: "Caspases: the executioners of apoptosis." in: The Biochemical journal, Vol. 326 ( Pt 1), Issue 5693, pp. 1-16, (1997) (PubMed).
: "In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 15, pp. 7464-9, (1996) (PubMed).
Synonyms and alternative names related to Caspase 10
caspase 10 S homeolog (casp10.S), caspase 10 (casp10), caspase 10 (CASP10), caspase 10 (Casp10), caspase-10 (LOC100848685), alps2, ALPS2, caspace-10, caspase-10, flice2, FLICE2, mch4, MCH4, xCaspace-10, xCaspase-10Protein level used designations for Caspase 10
- caspase-10
- caspase 10, apoptosis-related cysteine protease
- CASP-10
- FADD-like ICE2
- FAS-associated death domain protein interleukin-1B-converting enzyme 2
- ICE-like apoptotic protease 4
- apoptotic protease MCH-4
- interleukin-1B-converting enzyme 2
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