Caspase 6 产品
(Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
Categories
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq, Jul 2008].
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Featured Caspase 6 Categories
Caspase 6 抗体
High quality antibodies with extensive validation data.
Caspase 6 ELISA试剂盒
Reliable ELISA kits for a wide range of species.
Caspase 6 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Caspase 6 抗体
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Reactivity
Application
Validations
Cat. No.
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Datasheet
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Cow
Application
WB, IHC, ICC, IP
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- (6)
Cat. No.
ABIN7437107
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow
Application
WB, IHC, ICC, IP
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- (5)
Cat. No.
ABIN7437551
Quantity
100 μL
Datasheet
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Reactivity
Human
Application
WB, ELISA, ICC, FACS
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Cat. No.
ABIN7193443
Quantity
0.1 mg
Datasheet
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Recommended Caspase 6 ELISA试剂盒
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Reactivity
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Cat. No.
ABIN6965470
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Cat. No.
ABIN6954422
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96 tests
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Quantitative Competition ELISA
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Recommended Caspase 6 蛋白
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Cat. No.
ABIN3090652
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1 mg
Datasheet
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Reactivity
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ABIN3131297
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Latest Publications for our Caspase 6 Products
: "Automating cell detection and classification in human brain fluorescent microscopy images using dictionary learning and sparse coding." in: Journal of neuroscience methods, Vol. 282, pp. 20-33, (2017) (PubMed).: "Changes in phosphatidylinositol 3-kinase 55 kDa gamma expression and subcellular localization may be caspase 6 dependent in paraquat-induced SH-SY5Y apoptosis." in: Human & experimental toxicology, Vol. 33, Issue 7, pp. 761-71, (2015) (PubMed).
: "Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion." in: The Journal of clinical investigation, Vol. 124, Issue 3, pp. 1173-86, (2014) (PubMed).
: "Activity of the hypoxia-activated pro-drug TH-302 in hypoxic and perivascular regions of solid tumors and its potential to enhance therapeutic effects of chemotherapy." in: International journal of cancer, Vol. 134, Issue 11, pp. 2726-34, (2014) (PubMed).
: "Differential regulation of c-Jun protein plays an instrumental role in chemoresistance of cancer cells." in: The Journal of biological chemistry, Vol. 288, Issue 27, pp. 19321-9, (2013) (PubMed).
: "Use of molecular biomarkers to quantify the spatial distribution of effects of anticancer drugs in solid tumors." in: Molecular cancer therapeutics, Vol. 12, Issue 4, pp. 542-52, (2013) (PubMed).
: "An EGFR inhibitor enhances the efficacy of SN38, an active metabolite of irinotecan, in SN38-refractory gastric carcinoma cells." in: British journal of cancer, (2011) (PubMed).
: "Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 41, pp. 13729-38, (2010) (PubMed).
: "Neutrophils activate alveolar macrophages by producing caspase-6-mediated cleavage of IL-1 receptor-associated kinase-M." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 1, pp. 403-10, (2010) (PubMed).
: "Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34337-47, (2010) (PubMed).
Synonyms and alternative names related to Caspase 6
caspase 6 L homeolog (casp6.L), caspase 6 (casp6), caspase 6, apoptosis-related cysteine peptidase (casp6), group XIIA secretory phospholipase A2 (CASP6), caspase-6 (CpipJ_CPIJ017008), caspase 6 (Casp6), caspase 6 (CASP6), CASP6, casp6, caspase-6, mCASP-6, mch2, Mch2, MCH2, xCaspase-6, zgc:112960Protein level used designations for Caspase 6
- caspase-6
- caspase 6, apoptosis-related cysteine protease
- caspase-6a
- caspase 6
- Caspase-6
- CASP-6
- apoptotic protease Mch-2
- apoptotic protease MCH-2
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