CSNK1A1 Protein (GST tag)
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- 抗原 See all CSNK1A1 蛋白
- CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This CSNK1A1 protein is labelled with GST tag.
- 原理
- Recombinant Human CSNK1A1/CKI-alpha/CK1 Protein (GST Tag)(Active)
- 序列
- Met 1-Phe 337
- 产品特性
- A DNA sequence encoding the full length of human CSNK1A1 isoform 1 (P48729-1) (Met 1-Phe 337) was expressed with the GST tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- The specific activity was determined to be 30 nmol/min/mg using casein as substrate.
- Top Product
- Discover our top product CSNK1A1 蛋白
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Casein Kinase 1, alpha 1 (CSNK1A1) (AA 1-337) (Active) protein (GST tag)
CSNK1A1 宿主: 人 宿主: Insect Cells Recombinant SDS, Func Active
Casein Kinase 1, alpha 1 (CSNK1A1) (AA 1-365) (Active) protein (His-GST)CSNK1A1 宿主: 人 宿主: Insect cells (Sf9) Recombinant SDS, Func Active
Casein Kinase 1, alpha 1 (CSNK1A1) (AA 237-337) protein (GST tag)CSNK1A1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Casein Kinase 1, alpha 1 (CSNK1A1) (AA 1-337) protein (GST tag)CSNK1A1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Casein Kinase 1, alpha 1 (CSNK1A1) (AA 2-337) protein (His tag)Crystallography grade CSNK1A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Casein Kinase 1, alpha 1 (CSNK1A1) (AA 2-337) protein (His tag)Crystallography grade CSNK1A1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Casein Kinase 1, alpha 1 (CSNK1A1) (AA 1-337) protein (His tag)CSNK1A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % by SDS - PAGE SDS
Casein Kinase 1, alpha 1 (CSNK1A1) proteinCSNK1A1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile 20 mM Tris, 500 mM NaCl, 2 mM GSH, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))
- 别名
- CSNK1A1/CKI-alpha/CK1 (CSNK1A1 产品)
- 别名
- CK1 Protein, CK1a Protein, CKIa Protein, HLCDGP1 Protein, PRO2975 Protein, 2610208K14Rik Protein, 4632404G05Rik Protein, 5430427P18Rik Protein, Csnk1a Protein, CHUNP6894 Protein, ck1alpha Protein, wu:fb65a02 Protein, wu:fi30h04 Protein, wu:fj19c11 Protein, zgc:92158 Protein, KER1 Protein, ck1 Protein, CKIALPHA Protein, CK-II Protein, CSNK2A1 Protein, CG2028 Protein, CK I Protein, CK1alpha Protein, CKI Protein, CKI alpha Protein, CKIalpha Protein, CkIa Protein, Dmel\\CG2028 Protein, PKA-C Protein, anon-WO03040301.93 Protein, anon-WO03040301.95 Protein, ck1a Protein, dmCK1 Protein, dmckI Protein, l(1)G0492 Protein, casein kinase 1 alpha 1 Protein, casein kinase 1, alpha 1 Protein, keratin 1 Protein, casein kinase 1 alpha 1 L homeolog Protein, casein kinase 2 alpha 1 Protein, Casein kinase Ialpha Protein, CSNK1A1 Protein, Csnk1a1 Protein, csnk1a1 Protein, KRT1 Protein, csnk1a1.L Protein, CSNK2A1 Protein, CkIalpha Protein
- 背景
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Background: Casein kinase I isoform alpha, also known as CKI-alpha, CK1 and CSNK1A1, is a cytoplasm protein which belongs to the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. High expression of CSNK2A1, or concomitantly high expression of CSNK2A1, are independent prognostic factors of poor survival in NSCLC patients. CSNK2A1 are useful prognosis markers in non-small cell lung cancer (NSCLC) patients after complete resection, independent of lymph node metastasis status. CSNK1A1 can phosphorylate a large number of proteins. It participates in Wnt signaling. It phosphorylates CTNNB1 at 'Ser-45'. CSNK1A1 may play a role in segregating chromosomes during mitosis.
Synonym: CK1;CK1a;CKIa;HEL-S-77p;HLCDGP1;PRO2975
- 分子量
- 65.2 kDa
- 途径
- WNT signaling, Hedgehog Signaling
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