CAMK2A Protein (GST tag)
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- 抗原 See all CAMK2A 蛋白
- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This CAMK2A protein is labelled with GST tag.
- 原理
- Recombinant Human CAMK2A/CAMKA Protein (GST Tag)(Active)
- 序列
- Met 1-His 478
- 产品特性
- A DNA sequence encoding the human CAMK2A isoform 2 (NP_741960.1) (Met 1-His 478) was fused with the GST tag at the N-terminus.
- 纯度
- > 85 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- The specific activity was determined to be 160 nmol/min/mg using Autocamtide-2 synthetic peptide (KKALRRQETVDAL-amide) as substrate.
- Top Product
- Discover our top product CAMK2A 蛋白
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Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 1-478) protein (GST tag)
CAMK2A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 305-410) protein (GST tag)CAMK2A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 1-478) protein (Strep Tag)Crystallography grade CAMK2A 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (AA 1-478) protein (Strep Tag)Crystallography grade CAMK2A 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CAMK2A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CAMK2A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile 50 mM Tris, 100 mM NaCl, 0.5 mM PMSF, 0.5 mM Reduced Glutathione, pH 8.0
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
- 别名
- CAMK2A/CAMKA (CAMK2A 产品)
- 别名
- camk2 Protein, camk2b Protein, zgc:112538 Protein, zgc:123320 Protein, CAMKA Protein, CaMKII Protein, R74975 Protein, mKIAA0968 Protein, PK2CDD Protein, PKCCD Protein, calcium/calmodulin dependent protein kinase II alpha Protein, calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog Protein, calcium/calmodulin-dependent protein kinase II alpha Protein, CAMK2A Protein, camk2a.S Protein, camk2a Protein, Camk2a Protein
- 背景
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Background: Ca2+/calmodulin-dependent protein kinase2A (CAMK2A) belongs to the serine/threonine protein kinase family and, together with other 28 different isoforms, belongs to the Ca2+/ calmodulin-dependent protein kinase subfamily. CaM kinase II is thought to be an important mediator of learning and memory and is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CAMKIIA is one of the major forms of CAMKII. It has been found to play a critical role in sustaining activation of CAMKII at the postsynaptic density. Studies have found that knockout mice without CAMKIIA demonstrate a low frequency of LTP. Additionally, these mice do not form persistent, stable place cells in the hippocampus.
Synonym: CAMKA
- 分子量
- 80.3 kDa
- NCBI登录号
- NP_741960
- 途径
- WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction
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