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CAMK2A 产品

(Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

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The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008].

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Featured CAMK2A Categories

CAMK2A 抗体

High quality antibodies with extensive validation data.

CAMK2A ELISA试剂盒

Reliable ELISA kits for a wide range of species.

CAMK2A 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CAMK2A 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7435484
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, PLA
Validations
  • (5)
Cat. No. ABIN513973
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (5)
Cat. No. ABIN513972
Quantity 100 μg
Datasheet Datasheet

Recommended CAMK2A ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954282
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965328
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954281
Quantity 96 tests
Datasheet Datasheet

Recommended CAMK2A 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1347927
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1347925
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7317100
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our CAMK2A Products

Koene, van Grondelle, Proietti Onori, Wallaard, Kooijman, van Oort, Schreiber, Elgersma: "Effects of antiepileptic drugs in a new TSC/mTOR-dependent epilepsy mouse model." in: Annals of clinical and translational neurology, Vol. 6, Issue 7, pp. 1273-1291, (2019) (PubMed).

Schiapparelli, Shah, Ma, McClatchy, Sharma, Li, Yates, Goldberg, Cline: "The Retinal Ganglion Cell Transportome Identifies Proteins Transported to Axons and Presynaptic Compartments in the Visual System In Vivo." in: Cell reports, Vol. 28, Issue 7, pp. 1935-1947.e5, (2019) (PubMed).

Liu, McClatchy, Schiapparelli, Shen, Yates, Cline: "Role of the visual experience-dependent nascent proteome in neuronal plasticity." in: eLife, Vol. 7, (2018) (PubMed).

Royer, Herzog, Kenny, Tzvetkova, Cochrane, Marr, Paradis: "The Ras-like GTPase Rem2 is a potent inhibitor of calcium/calmodulin-dependent kinase II activity." in: The Journal of biological chemistry, Vol. 293, Issue 38, pp. 14798-14811, (2018) (PubMed).

Cai, Kasikara, Doran, Ramakrishnan, Birge, Tabas: "MerTK signaling in macrophages promotes the synthesis of inflammation resolution mediators by suppressing CaMKII activity." in: Science signaling, Vol. 11, Issue 549, (2018) (PubMed).

Fang, Li, Huang, Zhang, Chen, Zhang, Ding, Shi, Lu, Yang: "Traumatic Stress Produces Distinct Activations of GABAergic and Glutamatergic Neurons in Amygdala." in: Frontiers in neuroscience, Vol. 12, pp. 387, (2018) (PubMed).

Guiraud, Edwards, Squire, Babbs, Shah, Berg, Chen, Davies: "Identification of serum protein biomarkers for utrophin based DMD therapy." in: Scientific reports, Vol. 7, pp. 43697, (2018) (PubMed).

Ersoy, Maner-Smith, Li, Alpertunga, Cohen: "Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress." in: The Journal of clinical investigation, Vol. 128, Issue 1, pp. 141-156, (2017) (PubMed).

Doran, Ozcan, Cai, Zheng, Fredman, Rymond, Dorweiler, Sluimer, Hsieh, Kuriakose, Tall, Tabas: "CAMKIIγ suppresses an efferocytosis pathway in macrophages and promotes atherosclerotic plaque necrosis." in: The Journal of clinical investigation, Vol. 127, Issue 11, pp. 4075-4089, (2017) (PubMed).

Li, You, Zhang, Huang, Zou, Jie, Li, Liu, Lv, Cong, Hu, Gao, Li: "Satb2 Ablation Impairs Hippocampus-Based Long-Term Spatial Memory and Short-Term Working Memory and Immediate Early Genes (IEGs)-Mediated Hippocampal Synaptic Plasticity." in: Molecular neurobiology, (2017) (PubMed).

Synonyms and alternative names related to CAMK2A

calcium/calmodulin dependent protein kinase II alpha (CAMK2A), calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog (camk2a.S), calcium/calmodulin-dependent protein kinase II alpha (camk2a), calcium/calmodulin-dependent protein kinase II alpha (Camk2a), calcium/calmodulin dependent protein kinase II alpha (Camk2a), camk2, camk2b, CAMKA, CaMKII, mKIAA0968, PK2CDD, PKCCD, R74975, zgc:112538, zgc:123320

Protein level used designations for CAMK2A

  • calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha
  • calcium/calmodulin-dependent protein kinase II beta
  • calmodulin dependent protein kinase II beta subunit
  • calcium/calmodulin-dependent protein kinase II alpha
  • calcium/calmodulin-dependent protein kinase type II subunit alpha
  • camk2a1
  • CaM kinase II alpha subunit
  • CaM-kinase II alpha chain
  • CaMK-II alpha subunit
  • CaMKIINalpha
  • caM kinase II subunit alpha
  • caMK-II subunit alpha
  • calcium/calmodulin-dependent protein kinase II alpha-B subunit
  • calcium/calmodulin-dependent protein kinase type II alpha chain
  • CaMK II
  • alpha-CaMKII
  • Ca2+/calmodulin-dependent protein kinase II alpha
  • alpha CaM kinase II
  • caM-kinase II alpha chain
  • calcium/calmodulin-dependent protein kinase II alpha subunit
  • calcium/calmodulin-dependent protein kinase type II alpha
  • Calcium/calmodulin-dependent protein kinase type II alpha chain
  • calcium/calmodulin-dependent protein kinase IIA
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