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BAX Protein (His tag)

BAX 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318194
发货至: 中国
  • 抗原 See all BAX 蛋白
    BAX (BCL2-Associated X Protein (BAX))
    蛋白类型
    Recombinant
    宿主
    • 7
    • 4
    • 2
    • 2
    • 2
    资源
    • 11
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This BAX protein is labelled with His tag.
    原理
    Recombinant Human BAX/BCL2L4 Protein (His Tag)
    序列
    Met 1-Gln171
    产品特性
    Recombinant Human BCL2-associated X protein is produced by our E.coli expression system and the target gene encoding Met1-Gln171 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product BAX 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,2 mM EDTA,5 % Threhalose,30 % Glycerol, pH 7.4.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    BAX (BCL2-Associated X Protein (BAX))
    别名
    BAX/BCL2L4 (BAX 产品)
    别名
    BAX-ALPHA Protein, bax-A Protein, xBax Protein, xlbax Protein, BAX Protein, bax Protein, fj16e01 Protein, wu:fc50b10 Protein, wu:fj16e01 Protein, BCL2L4 Protein, zgc:112983 Protein, BCL2 associated X, apoptosis regulator Protein, BCL2-associated X protein L homeolog Protein, BCL2-associated X protein Protein, bcl2-associated X protein, a Protein, bcl2-associated X protein, b Protein, BAX Protein, bax.L Protein, bax Protein, baxa Protein, Bax Protein, baxb Protein
    背景

    Background: Apoptosis Regulator BAX (BAX) belongs to the Bcl-2 family. BAX exists as a homodimer and is expressed in a wide variety of tissues. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa). Although both isoforms contain BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. BAX accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. BAX also promotes activation of CASP3, and thereby apoptosis.

    Synonym: Apoptosis Regulator BAX, Bcl-2-Like Protein 4, Bcl2-L-4, BAX, BCL2L4

    分子量
    22.1 kDa
    UniProt
    Q07812
    途径
    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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